trifluoromethyl 4-methoxybenzenesulfonate

Base Information Edit

Chemical Name:trifluoromethyl 4-methoxybenzenesulfonate
CAS No.:1197209-28-1
Molecular Formula:C₈H₇F₃O₄S
Molecular Weight:256.202
Hs Code.:
Mol file:1197209-28-1.mol

Synonyms:trifluoromethyl 4-methoxybenzenesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of trifluoromethyl 4-methoxybenzenesulfonate Edit

Chemical Property:

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Technology Process of trifluoromethyl 4-methoxybenzenesulfonate

There total 3 articles about trifluoromethyl 4-methoxybenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 887144-97-0
Togni's reagent

: 5857-42-1
4-methoxybenzenesulfonic acid

: 1197209-28-1
trifluoromethyl 4-methoxybenzenesulfonate

Guidance literature:: In chloroform; tert-butyl alcohol; at 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.9b03000

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1197209-28-1
trifluoromethyl 4-methoxybenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-dioxane; water / 5 h / 100 °C

2: chloroform; tert-butyl alcohol / 20 °C / Inert atmosphere

In 1,4-dioxane; chloroform; water; tert-butyl alcohol;
DOI:10.1021/acs.orglett.9b03000