alpha-Cyclopentylmandelic acid, (+)-

Base Information Edit

Chemical Name:alpha-Cyclopentylmandelic acid, (+)-
CAS No.:64471-45-0
Molecular Formula:C₁₃H₁₆O₃
Molecular Weight:220.268
Hs Code.:
UNII:GPQ2NHD98V
DSSTox Substance ID:DTXSID70214733
Nikkaji Number:J1.152.306D
Wikidata:Q27279221
Mol file:64471-45-0.mol

Synonyms:64471-45-0;(R)-2-Cyclopentyl-2-hydroxy-2-phenylacetic acid;alpha-Cyclopentylmandelic acid, (+)-;GPQ2NHD98V;(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid;(R)-alpha-Cyclopentylmandelic Acid;UNII-GPQ2NHD98V;starbld0009287;SCHEMBL418664;DTXSID70214733;WFLUEQCOAQCQLP-ZDUSSCGKSA-N;(+)-alpha-cyclopentylmandelic acid;(R)-cyclopentylhydroxyphenylacetic acid;(R)-cyclopentylhydroxyphenyl acetic acid;(2R)-cyclopentyl(hydroxy)phenylacetic acid;(R)-Cyclopentyl-hydroxy-phenyl-acetic acid;(R)-.ALPHA.-CYCLOPENTYLMANDELIC ACID;CS-0120801;.ALPHA.-CYCLOPENTYLMANDELIC ACID, (+)-;Q27279221;(R)-2-CYCLOPENTYL-2-HYDROXY-2-(PHENYL)ACETIC ACID;BENZENEACETIC ACID, .ALPHA.-CYCLOPENTYL-.ALPHA.-HYDROXY-, (R)-;BENZENEACETIC ACID, .ALPHA.-CYCLOPENTYL-.ALPHA.-HYDROXY-, (.ALPHA.R)-

Suppliers and Price of alpha-Cyclopentylmandelic acid, (+)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of alpha-Cyclopentylmandelic acid, (+)- Edit

Chemical Property:

Melting Point:121-122 °C
Boiling Point:395.6±22.0 °C(Predicted)
Density:1.247±0.06 g/cm3(Predicted)
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:252

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(C1)C(C2=CC=CC=C2)(C(=O)O)O
Isomeric SMILES:C1CCC(C1)[C@@](C2=CC=CC=C2)(C(=O)O)O
Uses (R)-α-Cyclopentylmandelic Acid is used in chiral ligand exchange high-speed countercurrent chromatography and application in enantioseparation of aromatic α-hydroxyl acids.

Technology Process of alpha-Cyclopentylmandelic acid, (+)-

There total 25 articles about alpha-Cyclopentylmandelic acid, (+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 185030-09-5
(R)-α-(cyclopentyl-1-ene)-α-hydroxyl-α-phenylacetic acid

: 64471-45-0
(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; for 8h; under 760.051 Torr;

Reference yield: 83.4%

: 427-49-6
2-cyclopentyl-2-hydroxy-2-phenylacetic acid

: 64471-45-0
(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid

Guidance literature:: 2-cyclopentyl-2-hydroxy-2-phenylacetic acid; With D-tyrosine methyl ester; In water; acetonitrile; at 0 ℃; for 4h; Reflux;

With hydrogenchloride; In water; toluene; at 40 ℃;

Reference yield: 62.0%

: 937179-77-6
cis-(2S,5S)-2-(tert-butyl)-5-phenyl-5-cyclopentyl-1,3-dioxolan-4-one

: 64471-45-0
(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid

Guidance literature:: cis-(2S,5S)-2-(tert-butyl)-5-phenyl-5-cyclopentyl-1,3-dioxolan-4-one; With potassium hydroxide; In methanol; water; at 65 ℃; for 3 - 4h;

With hydrogenchloride; In water; ethyl acetate; pH=1;
DOI:10.1691/ph.2008.7775