3-CHLORO-5-IODOBENZOIC ACID

Base Information

• Chemical Name: 3-CHLORO-5-IODOBENZOIC ACID
• CAS No.: 289039-25-4
• Molecular Formula: C7H4ClIO2
• Molecular Weight: 282.465
• Hs Code.: 2916399090
• Mol file: 289039-25-4.mol

Synonyms:5-Chloro-3-iodobenzoic acid;

Chemical Property of 3-CHLORO-5-IODOBENZOIC ACID

Chemical Property:

• Vapor Pressure: 7.94E-06mmHg at 25°C
• Melting Point: 190-191℃
• Refractive Index: 1.673
• Boiling Point: 360.5 °C at 760 mmHg
• Flash Point: 171.8 °C
• PSA: 37.30000
• Density: 2.077 g/cm³
• LogP: 2.64280
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%min ^*data from raw suppliers

3-Chloro-5-iodobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-CHLORO-5-IODOBENZOIC ACID

There total 3 articles about 3-CHLORO-5-IODOBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-5-iodobenzoic acid methyl ester (289039-85-6) → 3-chloro-5-iodobenzoic acid (289039-25-4)

Guidance literature:

3-chloro-5-iodobenzoic acid methyl ester; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 1h;

In water; pH=4; Acidic aqueous solution;

Reference yield:

3-amino-5-chloro-benzoic acid (21961-30-8) → 3-chloro-5-iodobenzoic acid (289039-25-4)

Guidance literature:

With potassium disulphite; nitric acid; Diazotization_.nachfolgend Behandlung mit Jod-Kaliumjodid-Loesung;

Reference yield:

3-acetamido-5-chlorobenzoic acid (58123-67-4) → 3-chloro-5-iodobenzoic acid (289039-25-4)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated hydrochloric acid

2: nitric acid; potassium pyrosulfite / <0 / Diazotization_.nachfolgend Behandlung mit Jod-Kaliumjodid-Loesung

With hydrogenchloride; potassium disulphite; nitric acid;

upstream raw materials:

3-amino-5-chloro-benzoic acid

3-acetamido-5-chlorobenzoic acid

3-chloro-5-iodobenzoic acid methyl ester

Downstream raw materials:

1,1-dimethylethyl 3-chloro-5-iodobenzoate

1,1-dimethylethyl 3-chloro-5-(2,4-dimethyl-1H-imidazol-1-yl)benzoate

3-chloro-5-(2,4-dimethyl-1H-imidazol-1-yl)benzoic acid

3-chloro-5-phenylbenzoic acid

Refernces