L-ARGININE T-BUTYL ESTER DIHYDROCHLORIDE

Base Information

• Chemical Name: L-ARGININE T-BUTYL ESTER DIHYDROCHLORIDE
• CAS No.: 87459-72-1
• Molecular Formula: C₁₀H₂₂N₄O₂*2ClH
• Molecular Weight: 303.232
• Hs Code.: 2925290090
• Mol file: 87459-72-1.mol

Synonyms:L-Arginine,1,1-dimethylethyl ester, dihydrochloride (9CI);H-Arg-OtBu.2HCl;H-Arg-OtBu·2HCl;

Chemical Property of L-ARGININE T-BUTYL ESTER DIHYDROCHLORIDE

Chemical Property:

• PSA: 114.22000
• LogP: 3.41390
• Storage Temp.: Store at 0°C

Purity/Quality:

99% ^*data from raw suppliers

H-Arg-OtBu 2HCl 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-ARGININE T-BUTYL ESTER DIHYDROCHLORIDE

There total 2 articles about L-ARGININE T-BUTYL ESTER DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

Z-Arg(NO2)-OBut (120609-77-0) → H-Arg-OBut*2HCl (87459-72-1)

Guidance literature:

With hydrogen; acetic acid; palladium on activated charcoal; In methanol; water; under 827.4 Torr;

DOI:10.1021/jm00127a041

Reference yield:

N5-[imino(nitroamino)methyl]-N2-[(phenylmethoxy)carbonyl]-L-ornithine (2304-98-5) → H-Arg-OBut*2HCl (87459-72-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) dicyclohexylcarbodiimide, copper(II) chloride / 1.) 65 h, 2.) ethyl acetate, 65 h

2: 61 percent / H₂, acetic acid / 10 percent Pd/C / methanol; H₂O / 827.4 Torr

With hydrogen; acetic acid; dicyclohexyl-carbodiimide; copper dichloride; palladium on activated charcoal; In methanol; water;

DOI:10.1021/jm00127a041

upstream raw materials:

Z-Arg(NO₂)-OBu^t

N₅-[imino(nitroamino)methyl]-N₂-[(phenylmethoxy)carbonyl]-L-ornithine

Refernces