Technology Process of C14H20O3
There total 4 articles about C14H20O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
ethyl acetate;
at 20 ℃;
for 10h;
under 760.051 Torr;
Inert atmosphere;
DOI:10.1021/ja1103102
- Guidance literature:
-
2-Methyl-2-(1-methylethyl)-1,3-propandiol;
With
2,6-bis((S)-3,3-dibutyl-2-phenyl-3,4-dihydro-2H-pyrrol-5-yl)pyridine; copper dichloride;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
benzoyl chloride;
With
triethylamine;
In
dichloromethane;
at -78 ℃;
for 5h;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
DOI:10.1021/ja1103102
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 2,6-bis((S)-3,3-dibutyl-2-phenyl-3,4-dihydro-2H-pyrrol-5-yl)pyridine; copper dichloride / dichloromethane / 20 °C / Inert atmosphere
1.2: 12 h / -78 °C / Inert atmosphere
2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 10 h / 20 °C / 760.05 Torr / Inert atmosphere
With
palladium 10% on activated carbon; 2,6-bis((S)-3,3-dibutyl-2-phenyl-3,4-dihydro-2H-pyrrol-5-yl)pyridine; hydrogen; copper dichloride;
In
dichloromethane; ethyl acetate;
DOI:10.1021/ja1103102