C₃₉H₅₇NO₆S₂Si

Base Information

• Chemical Name: C₃₉H₅₇NO₆S₂Si
• CAS No.: 1380242-13-6
• Molecular Formula: C₃₉H₅₇NO₆S₂Si
• Molecular Weight: 728.102
• Mol file: 1380242-13-6.mol

Synonyms:C₃₉H₅₇NO₆S₂Si

Chemical Property of C₃₉H₅₇NO₆S₂Si

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of C₃₉H₅₇NO₆S₂Si

There total 8 articles about C₃₉H₅₇NO₆S₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C27H44O3S2Si (1380242-12-5) + (4S)-4-benzyl-3-propionyl-1,3-oxazolidin-2-one (184363-66-4) → C39H57NO6S2Si (1380242-13-6)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; titanium tetrachloride; sparteine; In dichloromethane; at -78 - 0 ℃; for 2h; Inert atmosphere;

DOI:10.1002/anie.201201395

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) → C39H57NO6S2Si (1380242-13-6)

Guidance literature:

Multi-step reaction with 6 steps

1: triethylamine / dichloromethane / 1 h / Cooling with ice

2: N,N,N,N,N,N-hexamethylphosphoric triamide; tert.-butyl lithium / tetrahydrofuran; pentane / 0.5 h / -78 - -40 °C / Inert atmosphere

3: sodium hexamethyldisilazane / tetrahydrofuran; N,N-dimethyl-formamide / 2 h / -10 °C / Inert atmosphere

4: camphor-10-sulfonic acid / methanol; dichloromethane / 1 h / -10 °C

5: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / dichloromethane / 2 h / Cooling with ice; Inert atmosphere

6: 1-methyl-pyrrolidin-2-one; titanium tetrachloride; sparteine / dichloromethane / 2 h / -78 - 0 °C / Inert atmosphere

With 1-methyl-pyrrolidin-2-one; N,N,N,N,N,N-hexamethylphosphoric triamide; camphor-10-sulfonic acid; tert.-butyl lithium; sodium hexamethyldisilazane; sulfur trioxide pyridine complex; titanium tetrachloride; dimethyl sulfoxide; triethylamine; sparteine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; pentane;

DOI:10.1002/anie.201201395

Reference yield:

C15H30OS2Si (1306602-89-0) → C39H57NO6S2Si (1380242-13-6)

Guidance literature:

Multi-step reaction with 5 steps

1: N,N,N,N,N,N-hexamethylphosphoric triamide; tert.-butyl lithium / tetrahydrofuran; pentane / 0.5 h / -78 - -40 °C / Inert atmosphere

2: sodium hexamethyldisilazane / tetrahydrofuran; N,N-dimethyl-formamide / 2 h / -10 °C / Inert atmosphere

3: camphor-10-sulfonic acid / methanol; dichloromethane / 1 h / -10 °C

4: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / dichloromethane / 2 h / Cooling with ice; Inert atmosphere

5: 1-methyl-pyrrolidin-2-one; titanium tetrachloride; sparteine / dichloromethane / 2 h / -78 - 0 °C / Inert atmosphere

With 1-methyl-pyrrolidin-2-one; N,N,N,N,N,N-hexamethylphosphoric triamide; camphor-10-sulfonic acid; tert.-butyl lithium; sodium hexamethyldisilazane; sulfur trioxide pyridine complex; titanium tetrachloride; dimethyl sulfoxide; triethylamine; sparteine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; pentane;

DOI:10.1002/anie.201201395

upstream raw materials:

C₁₅H₃₀OS₂Si

C₁₆H₁₉NO₃S

C₉H₁₆OS₂

C₂₆H₅₄O₃S₂Si₂

Downstream raw materials:

C₃₀H₃₇NO₇

C₅₀H₆₇NO₁₁

C₅₀H₆₇NO₁₁

C₃₆H₅₁NO₇Si

Refernces