Propionamidine hydrochloride

Base Information

• Chemical Name: Propionamidine hydrochloride
• CAS No.: 39800-84-5
• Molecular Formula: C3H8N2
• Molecular Weight: 108.57
• Mol file: 39800-84-5.mol

Synonyms:Propionamidine;Propaneimidamide;

Chemical Property of Propionamidine hydrochloride

Chemical Property:

• Boiling Point: 90.8±23.0 °C(Predicted)
• PKA: 12.49±0.40(Predicted)
• PSA: 49.87000
• Density: 0.99±0.1 g/cm3(Predicted)
• LogP: 1.13240
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Propanimidamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propionamidine hydrochloride

There total 6 articles about Propionamidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

propiononitrile (107-12-0) → propamidine (39800-84-5)

Guidance literature:

With trimethylaluminum; ammonium chloride; In toluene; at 20 ℃; for 1.5h;

propiononitrile; In toluene; at 85 ℃; for 9h;

Reference yield:

O-ethyl thiopropionate (924-45-8) → propamidine (39800-84-5)

Guidance literature:

With ammonia; ammonium chloride; In ethanol; Heating;

Reference yield:

→ propamidine (39800-84-5)

Guidance literature:

With ethanol; ammonia;

upstream raw materials:

O-ethyl thiopropionate

propiononitrile

ammonia

Downstream raw materials:

N-acetylpropionamide

N-Benzylpropionamidin

pentanimidamide

C₁₃H₁₄N₂O₂

Refernces

• 1、 -. "DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT". Page/Page column 133. . Retrieved 2010/11/24.
• 2、 -. "Pyrimidinone derivatives". . . Retrieved 2008/06/13.