2-(2'-HYDROXYETHYL)PYRAZINE

Base Information

• Chemical Name: 2-(2'-HYDROXYETHYL)PYRAZINE
• CAS No.: 6705-31-3
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.142
• Hs Code.: 2933990090
• Mol file: 6705-31-3.mol

Synonyms:Pyrazineethanol(7CI,8CI,9CI);(2-Hydroxyethyl)pyrazine;2-(2-Hydroxyethyl)pyrazine;2-Pyrazinylethyl alcohol;b-Pyrazinylethanol;

Chemical Property of 2-(2'-HYDROXYETHYL)PYRAZINE

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Refractive Index: 1.544
• Boiling Point: 235.809 °C at 760 mmHg
• PKA: 14.52±0.10(Predicted)
• Flash Point: 96.414 °C
• PSA: 46.01000
• Density: 1.169 g/cm³
• LogP: 0.01140
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

2-(Pyrazin-2-yl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 2-(2'-Hydroxyethyl)pyrazine is a chemical compound with potential applications in various fields. In the flavor and fragrance industry, it serves as an aroma compound, imparting a pleasant, nutty, and roasted scent or flavor to various food products, beverages, and perfumes. In organic synthesis, it can be used as an intermediate for the creation of more complex organic molecules, aiding in the development of novel materials, pharmaceuticals, or specialty chemicals. Additionally, in academic research, this compound may be employed as a reference material for studying reaction mechanisms and conducting studies in synthetic chemistry, contributing to advancements in the field. Its multifaceted contributions underscore its significance in flavor and fragrance, organic synthesis, and chemical research, playing various roles in enhancing the sensory experience of products, advancing material development, and facilitating scientific discovery.

Technology Process of 2-(2'-HYDROXYETHYL)PYRAZINE

There total 5 articles about 2-(2'-HYDROXYETHYL)PYRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylpyrazine (109-08-0) → 2-(2-hydroxyethyl)-pyrazine (6705-31-3)

Guidance literature:

With paraformaldehyde;

Reference yield:

(RS)-2-methylpiperazine (109-07-9) → 2-(2-hydroxyethyl)-pyrazine (6705-31-3)

Guidance literature:

Multi-step reaction with 2 steps

1: copper oxide-chromium oxide-aluminium oxide catalyst / 475 °C

With aluminum oxide; copper oxide-chromium oxide-aluminium oxide catalyst;

DOI:10.1021/ja01148a128

Reference yield:

2-Methylpyrazine (109-08-0) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 2-(2-hydroxyethyl)-pyrazine (6705-31-3)

Guidance literature:

DOI:10.1021/ja01148a128

upstream raw materials:

2-Methylpyrazine

formaldehyd

D-(+)-glucosamine hydrochloride

(RS)-2-methylpiperazine

Downstream raw materials:

7,8-dihydro-5H-pyrano[4,3-b]pyridine

3,4-Dihydro-1H-pyrano[4,3-c]pyridine

8-Trimethylsilanyl-3,4-dihydro-1H-pyrano[4,3-c]pyridine

4-Trimethylsilanyl-7,8-dihydro-5H-pyrano[4,3-b]pyridine

Refernces

• 1、 -. "N,N-diacylpiperazine tachykinin antagonists". . . Retrieved 2008/06/13.