(3R)-3-amino-1-hydroxypyrrolidin-2-one

Base Information Edit

Chemical Name:(3R)-3-amino-1-hydroxypyrrolidin-2-one
CAS No.:123931-04-4
Molecular Formula:C₄H₈N₂O₂
Molecular Weight:116.12
Hs Code.:
UNII:2N9Q4C7WMT
Nikkaji Number:J346.131I
Wikidata:Q27077966
ChEMBL ID:CHEMBL335231
Mol file:123931-04-4.mol

Synonyms:(R)-(+)-HA-966;123931-04-4;(3R)-3-amino-1-hydroxypyrrolidin-2-one;(+)-HA-966;(R)-HA-966;2N9Q4C7WMT;CHEMBL335231;HA-966, (R)-;(+)-HA966;1-Hydroxy-3-amino-pyrrolidine-2-one, (R)-;2-Pyrrolidinone, 3-amino-1-hydroxy-, (R)-;HA-966, (+)-;2-Pyrrolidinone, 3-amino-1-hydroxy-, (3R)-;(R) pound-(+)-3-Amino-1-hydroxypyrrolidin-2-one;R(+)-HA-966;R(+)-3-Amino-1-hydroxy-2-pyrrolidinone;Tocris-0281;Lopac-A-9699;Biomol-NT_000196;D08TAN;UNII-2N9Q4C7WMT;R(+)-HA-966, solid;BPBio1_001224;GTPL4066;SCHEMBL1897868;r-(+)-ha-966;HMS3266E15;HMS3411C19;HMS3675C19;BDBM50038159;AKOS006273851;(R)-3-amino-1-hydroxypyrrolidin-2-one;NCGC00015111-01;NCGC00024522-01;NCGC00024522-02;MS-22746;(R)-3-Amino-1-hydroxy-pyrrolidin-2-one;HA-966-(R)-(+);HY-100822;2-Pyrrolidinone,3-amino-1-hydroxy-,(3R)-;CS-0020466;(R)-(+)-3-Amino-1-hydroxypyrrolidin-2-one;SR-01000597725;J-005000;SR-01000597725-1;Q27077966

Suppliers and Price of (3R)-3-amino-1-hydroxypyrrolidin-2-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(+)-HA-966
50mg
$ 730.00

Tocris
(R)-(+)-HA-966 ≥98%(HPLC)
10
$ 161.00

Sigma-Aldrich
R(+)-HA-966 solid
5mg
$ 156.00

ApexBio Technology
(R)-(+)-HA-966
10mg
$ 234.00

American Custom Chemicals Corporation
(R)-(+)-HA-966 95.00%
10MG
$ 673.08

Total 12 raw suppliers

Chemical Property of (3R)-3-amino-1-hydroxypyrrolidin-2-one Edit

Chemical Property:

Appearance/Colour:White solid
Vapor Pressure:0.002mmHg at 25°C
Melting Point:166℃
Refractive Index:1.59
Boiling Point:258.6 °C at 760 mmHg
PKA:7.19±0.20(Predicted)
Flash Point:110.2 °C
PSA：66.56000
Density:1.436 g/cm³
LogP:-0.42660
Storage Temp.:Desiccate at RT
Solubility.:H2O: soluble
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:116.058577502
Heavy Atom Count:8
Complexity:115

Purity/Quality:

99% ^*data from raw suppliers

(R)-(+)-HA-966 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(=O)C1N)O
Isomeric SMILES:C1CN(C(=O)[C@@H]1N)O
Uses (R)-(+)-HA-966 is an antagonist/partial agonist at the glycine site of the NMDA receptor.

Technology Process of (3R)-3-amino-1-hydroxypyrrolidin-2-one

There total 11 articles about (3R)-3-amino-1-hydroxypyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%