1,4-Diethoxy-2,3,5,6-tetrafluorobenzene

Base Information

• Chemical Name: 1,4-Diethoxy-2,3,5,6-tetrafluorobenzene
• CAS No.: 16251-00-6
• Molecular Formula: C₁₀H₁₀F₄O₂
• Molecular Weight: 238.182
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID40382130
• Nikkaji Number: J3.123.658D
• Wikidata: Q82173446
• Mol file: 16251-00-6.mol

Synonyms:16251-00-6;1,4-diethoxy-2,3,5,6-tetrafluorobenzene;1,4-Bis(ethoxy)tetrafluorobenzene;1,4-Diethoxytetrafluorobenzene;Benzene, 1,4-diethoxy-2,3,5,6-tetrafluoro-;SCHEMBL16291780;DTXSID40382130;MFCD00804629;AKOS007930471;FT-0637342;A810380

Chemical Property of 1,4-Diethoxy-2,3,5,6-tetrafluorobenzene

Chemical Property:

• Vapor Pressure: 0.171mmHg at 25°C
• Melting Point: 49-49.5 °C
• Refractive Index: 1.434
• Boiling Point: 220 °C at 760 mmHg
• Flash Point: 93.6 °C
• PSA: 18.46000
• Density: 1.271 g/cm³
• LogP: 3.04040
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 238.06169221
• Heavy Atom Count: 16
• Complexity: 179

Purity/Quality:

98%min ^*data from raw suppliers

1,4-Diethoxytetrafluorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=C(C(=C(C(=C1F)F)OCC)F)F

Technology Process of 1,4-Diethoxy-2,3,5,6-tetrafluorobenzene

There total 2 articles about 1,4-Diethoxy-2,3,5,6-tetrafluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

Hexafluorobenzene (392-56-3) + sodium ethanolate (141-52-6) → 1,4-Diethoxy-tetrafluor-benzol (16251-00-6)

Guidance literature:

In ethanol; for 1h;

DOI:10.1016/S0022-1139(00)80901-X

Reference yield:

sodium ethanolate (141-52-6) + hexafluoro dewar benzene → 1,4-Diethoxy-tetrafluor-benzol (16251-00-6)

Guidance literature:

Multistep reaction; (i) EtOH, (ii) (heating);

DOI:10.1039/j39690000489

upstream raw materials:

sodium ethanolate

Hexafluorobenzene