(D-LEU2)-MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING FACTOR

Base Information

• Chemical Name: (D-LEU2)-MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING FACTOR
• CAS No.: 39705-60-7
• Molecular Formula: C₁₃H₂₄N₄O₃
• Molecular Weight: 284.359
• Mol file: 39705-60-7.mol

Synonyms:44:PN: US6093797 TABLE: 1 claimed protein;H-Pro-D-Leu-Gly-NH2;[D-Leu2]-Melanocyte-Stimulating Hormone-Release Inhibiting Factor;

Chemical Property of (D-LEU2)-MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING FACTOR

Chemical Property:

• Boiling Point: 626.2 °C at 760 mmHg
• Flash Point: 332.5 °C
• PSA: 113.32000
• Density: 1.147 g/cm³
• LogP: 0.68170
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

H-PRO-D-LEU-GLY-NH2 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (D-LEU2)-MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING FACTOR

There total 1 articles about (D-LEU2)-MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING FACTOR which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-(N-L-prolyl-L-leucyl)-glycin-amide (2002-44-0,39705-60-7,103225-11-2)

Guidance literature:

With hydrogen bromide; acetic acid;

DOI:10.1002/hlca.19550380622

Reference yield:

benzyloxycarbonyl-S-benzylcysteine (3257-18-9) + N-(N-L-prolyl-L-leucyl)-glycin-amide (2002-44-0,39705-60-7,103225-11-2) → S-benzyl-N-benzyloxycarbonyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide (16747-86-7)

Guidance literature:

With 1-ethyl-piperidine; chloroform; benzyl chloroformate;

Reference yield:

S-benzyl-N-[N2-(N2-benzyloxycarbonyl-L-glutaminyl)-L-asparaginyl]-L-cysteinyl azide (67470-42-2) + N-(N-L-prolyl-L-leucyl)-glycin-amide (2002-44-0,39705-60-7,103225-11-2) → N2-benzyloxycarbonyl-glutaminyl=>asparaginyl=>S-benzyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide (21688-11-9)

Guidance literature:

With N,N-dimethyl-formamide;

DOI:10.1002/hlca.19550380622

Downstream raw materials:

S-benzyl-N-benzyloxycarbonyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide

N²-benzyloxycarbonyl-glutaminyl=>asparaginyl=>S-benzyl-cysteinyl=>prolyl=>leucyl=>-glycin-amide