N-Methyl-N-nitrobenzylamine

Base Information

• Chemical Name: N-Methyl-N-nitrobenzylamine
• CAS No.: 36239-05-1
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.18
• Mol file: 36239-05-1.mol

Synonyms:N-Methyl-N-nitrobenzylamine

Chemical Property of N-Methyl-N-nitrobenzylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Methyl-N-nitrobenzylamine

There total 8 articles about N-Methyl-N-nitrobenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzyl-methyl-amine (103-67-3) → N-Methyl-N-nitrobenzylamine (36239-05-1)

Guidance literature:

With 4-chloro-5-methoxy-2-nitropyridazin-3-one; In dichloromethane; at 20 ℃; for 1h; Further Variations:; Reagents; Solvents; reaction times; Product distribution;

DOI:10.1021/jo0301503

Reference yield: 87.0%

Benzylmethylnitrosamin (937-40-6) → N-Methyl-N-nitrobenzylamine (36239-05-1)

Guidance literature:

With dihydrogen peroxide; In acetic acid; at 90 ℃; for 7h;

Reference yield:

N,N'-dimethylbenzylamine (103-83-3) → N-Methyl-N-nitrobenzylamine (36239-05-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / HNO₃ (70percent), acetic anhydride / 1.) 50 deg C, 30 min, 2.) room temp., 16 h

2: 87 percent / 30percent aq. H₂O₂ / acetic acid / 7 h / 90 °C

With dihydrogen peroxide; nitric acid; acetic anhydride; In acetic acid;

upstream raw materials:

methylnitroamine

benzyl bromide

sodium salt of methylnitramine

benzyl chloride

Downstream raw materials:

Potassium benzoate

benzaldehyde

methylamine

N-Benzylidenemethylamine

Refernces

• 1、 Masuda, Mitsuharu,Mower, Howard F.,Pignatelli, Brigitte,Celan, Irena,Friesen, Marlin D.,Nishino, Hoyoku,Ohshima, Hiroshi. "Formation of N-nitrosamines and N-nitramines by the reaction of secondary amines peroxynitrite and other reactive nitrogen species: Comparison with nitrotyrosine formation". . p. 301 - 308. Retrieved 2000.
• 2、 Boyer,Pillai,Ramakrishnan. "Nitrosamines and nitramines from tertiary amines". . p. 677 - 677. Retrieved 2007/10/02.