C₁₉H₂₁N

Base Information

• Chemical Name: C₁₉H₂₁N
• CAS No.: 1332371-41-1
• Molecular Formula: C₁₉H₂₁N
• Molecular Weight: 263.382
• Mol file: 1332371-41-1.mol

Synonyms:C₁₉H₂₁N

Chemical Property of C₁₉H₂₁N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₁N

There total 2 articles about C₁₉H₂₁N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-N-[2-(2-methyl-1H-inden-7-yl)ethyl]benzenesulfonamide (1332371-31-9) + benzyl chloride (100-44-7) → N-benzyl-2-(2-methyl-1H-inden-7-yl)ethanamine (1332371-40-0) + C19H21N (1332371-41-1)

Guidance literature:

4-methyl-N-[2-(2-methyl-1H-inden-7-yl)ethyl]benzenesulfonamide; benzyl chloride; With caesium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 80 ℃; for 24h;

With magnesium; In methanol; at 50 ℃; Reflux;

With oxalic acid; In methanol; Overall yield = 94 %; Overall yield = 5.94 g; Reflux;

Reference yield:

4(7)-bromo-2-methyl-1(3)H-indene (880652-93-7) → N-benzyl-2-(2-methyl-1H-inden-7-yl)ethanamine (1332371-40-0) + C19H21N (1332371-41-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: magnesium; iodine / tetrahydrofuran / 0.5 h / Reflux

1.2: 10 - 20 °C

2.1: caesium carbonate; potassium iodide / N,N-dimethyl-formamide / 24 h / 80 °C

2.2: 50 °C / Reflux

2.3: Reflux

With iodine; caesium carbonate; magnesium; potassium iodide; In tetrahydrofuran; N,N-dimethyl-formamide;

upstream raw materials:

4-methyl-N-[2-(2-methyl-1H-inden-7-yl)ethyl]benzenesulfonamide

benzyl chloride

4⁽⁷⁾-bromo-2-methyl-1⁽³⁾H-indene

Refernces