L-Kynurenine sulfate

Base Information

• Chemical Name: L-Kynurenine sulfate
• CAS No.: 13535-93-8
• Molecular Formula: C10H14N2O7S
• Molecular Weight: 306.29236
• Mol file: 13535-93-8.mol

Synonyms:L-KYNURENINE SULFATE;L-KYNURENINE SULFATE SALT;2-amino-4-(2-aminophenyl)-4-oxobutanoicacid,sulfuricacid;(S)-alpha,2-Diamino-gamma-oxobenzenebutanoic acid sulfate;L-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID SULFATE SALT

Chemical Property of L-Kynurenine sulfate

Chemical Property:

• Appearance/Colour: light yellow crystalline
• Boiling Point: 466.6 °C at 760 mmHg
• Flash Point: 236 °C
• PSA: 189.39000
• LogP: 1.96300
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

L-Kynurenine sulfate salt crystalline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Kynurenine sulfate

There total 5 articles about L-Kynurenine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(S)-4-(2-aminophenyl)-2-(((benzyloxy)carbonyl)amino)-4-oxobutanoic acid (1409999-05-8) → (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfate (16055-80-4,13535-93-8,17268-44-9)

Guidance literature:

(S)-4-(2-aminophenyl)-2-(((benzyloxy)carbonyl)amino)-4-oxobutanoic acid; With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In 1,4-dioxane; water;

With sulfuric acid;

DOI:10.1016/j.tetlet.2012.09.055

Reference yield:

C18H18N2O5 → (R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfate (21881-27-6,13535-93-8,17268-44-9)

Guidance literature:

C₁₈H₁₈N₂O₅; With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In 1,4-dioxane; water;

With sulfuric acid;

DOI:10.1016/j.tetlet.2012.09.055

Reference yield:

D-tryptophan (153-94-6,27732-43-0,80206-30-0,27813-82-7) → (R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfate (21881-27-6,13535-93-8,17268-44-9)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hydroxide / water / 0 - 20 °C

2: hydrogenchloride; dimethyl sulfoxide / water; acetic acid

3: sodium hydroxide / water

4: hydrogen; palladium 10% on activated carbon; hydrogenchloride / water; 1,4-dioxane

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; dimethyl sulfoxide; sodium hydroxide; In 1,4-dioxane; water; acetic acid;

DOI:10.1016/j.tetlet.2012.09.055

upstream raw materials:

(S)-2-(((benzyloxy)carbonyl)amino)-3-(2-oxoindolin-3-yl)propanoic acid

(S)-4-(2-aminophenyl)-2-(((benzyloxy)carbonyl)amino)-4-oxobutanoic acid

D-tryptophan

N-(benzyloxycarbonyl)-D-tryptophan

Refernces