C₂₃H₁₉BrN₂O₈S₂

Base Information

• Chemical Name: C₂₃H₁₉BrN₂O₈S₂
• CAS No.: 1395898-53-9
• Molecular Formula: C₂₃H₁₉BrN₂O₈S₂
• Molecular Weight: 595.448
• Mol file: 1395898-53-9.mol

Synonyms:C₂₃H₁₉BrN₂O₈S₂

Chemical Property of C₂₃H₁₉BrN₂O₈S₂

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₂₃H₁₉BrN₂O₈S₂

There total 2 articles about C₂₃H₁₉BrN₂O₈S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

6,7-dihydro-4H-thieno[3,2-c]pyran-2-carbaldehyde (623564-80-7) + (5R, 6S)-6-bromo-7-oxo-4-thia-l-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester (623564-82-9) + acetic anhydride (108-24-7) → C23H19BrN2O8S2 (1395898-53-9)

Guidance literature:

6,7-dihydro-4H-thieno[3,2-c]pyran-2-carbaldehyde; (5R, 6S)-6-bromo-7-oxo-4-thia-l-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester; With triethylamine; magnesium bromide; In tetrahydrofuran; acetonitrile; at -20 - 23 ℃; for 3.5h;

acetic anhydride; In tetrahydrofuran; acetonitrile; at 0 ℃; for 18h;

Reference yield: 41.0%

6,7-dihydro-4H-thieno[3,2-c]pyran-2-carbaldehyde (623564-80-7) + acetic anhydride (108-24-7) → C23H19BrN2O8S2 (1395898-53-9)

Guidance literature:

6,7-dihydro-4H-thieno[3,2-c]pyran-2-carbaldehyde; (5R, 6S)-6-bromo-7-oxo-4-thia-l-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester; With triethylamine; magnesium bromide; In tetrahydrofuran; acetonitrile; at -20 ℃; for 3h;

acetic anhydride; In tetrahydrofuran; acetonitrile; at -20 - 0 ℃; for 18h;

upstream raw materials:

6,7-dihydro-4H-thieno[3,2-c]pyran-2-carbaldehyde

acetic anhydride

(5R, 6S)-6-bromo-7-oxo-4-thia-l-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

Refernces

• 1、 -. "BICYCLIC 6-ALKYLIDENE-PENEMS AS ?-LACTAMASES INHIBITORS". Page/Page column 88-89. . Retrieved 2008/06/13.