Technology Process of 2,6-Dimethoxy-4-propylbenzeneacetaldehyde
There total 3 articles about 2,6-Dimethoxy-4-propylbenzeneacetaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1,3-dimethoxy-5-propylbenzene;
With
n-butyllithium;
In
hexane; cyclohexane;
for 1.5h;
Heating;
Bromoacetaldehyde diethyl acetal;
In
hexane; cyclohexane;
for 1.5h;
Heating;
With
hydrogenchloride;
In
ethanol;
at 20 ℃;
DOI:10.1002/1521-4184(200102)334:2<53::AID-ARDP53>3.0.CO;2-C
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: Mg / diethyl ether
1.2: 88 percent / diethyl ether / 2 h / Heating
2.1: 68 percent / H2 / 10 percent Pd/C / acetic acid / 30 h / 20 °C
3.1: nBuLi / cyclohexane; hexane / 1.5 h / Heating
3.2: cyclohexane; hexane / 1.5 h / Heating
3.3: 20 percent / HCl / ethanol / 20 °C
With
n-butyllithium; hydrogen; magnesium;
palladium on activated charcoal;
In
diethyl ether; hexane; cyclohexane; acetic acid;
1.2: Grignard reaction;
DOI:10.1002/1521-4184(200102)334:2<53::AID-ARDP53>3.0.CO;2-C
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 68 percent / H2 / 10 percent Pd/C / acetic acid / 30 h / 20 °C
2.1: nBuLi / cyclohexane; hexane / 1.5 h / Heating
2.2: cyclohexane; hexane / 1.5 h / Heating
2.3: 20 percent / HCl / ethanol / 20 °C
With
n-butyllithium; hydrogen;
palladium on activated charcoal;
In
hexane; cyclohexane; acetic acid;
DOI:10.1002/1521-4184(200102)334:2<53::AID-ARDP53>3.0.CO;2-C