TETRAHYDRO-FURAN-2-CARBOXAMIDINE HOAC

Base Information

• Chemical Name: TETRAHYDRO-FURAN-2-CARBOXAMIDINE HOAC
• CAS No.: 688000-41-1
• Molecular Formula: C₅H₁₀N₂O
• Molecular Weight: 114.147
• Mol file: 688000-41-1.mol

Synonyms:TETRAHYDRO-FURAN-2-CARBOXAMIDINE ACETIC ACID;TETRAHYDRO-FURAN-2-CARBOXAMIDINE HOAC

Chemical Property of TETRAHYDRO-FURAN-2-CARBOXAMIDINE HOAC

Chemical Property:

• Boiling Point: 353.4oC at 760 mmHg
• Flash Point: 167.5oC
• PSA: 96.40000
• LogP: 0.99230
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98% ^*data from raw suppliers

Tetrahydro-furan-2-carboxamidineaceticacid 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TETRAHYDRO-FURAN-2-CARBOXAMIDINE HOAC

There total 3 articles about TETRAHYDRO-FURAN-2-CARBOXAMIDINE HOAC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetrahydrofurane-2-carboximidate de methyle (135290-62-9) → tetrahydrofuran-2-carboximidamide (688000-41-1)

Guidance literature:

With ammonium chloride; In methanol; at 10 - 70 ℃; for 12h;

Reference yield:

tetrahydro-2-furancarboxylic acid (16874-33-2) → tetrahydrofuran-2-carboximidamide (688000-41-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 2 h / 15 °C

1.2: 2 h / 0 - 15 °C

2.1: dichloromethane / 12 h / 0 - 15 °C

3.1: ammonium chloride / methanol / 12 h / 10 - 70 °C

With ammonium chloride; 1,1'-carbonyldiimidazole; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

tetrahydrofuran-2-carboxamide (91470-28-9) → tetrahydrofuran-2-carboximidamide (688000-41-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 12 h / 0 - 15 °C

2: ammonium chloride / methanol / 12 h / 10 - 70 °C

With ammonium chloride; In methanol; dichloromethane;

upstream raw materials:

tetrahydro-2-furancarboxylic acid

tetrahydrofuran-2-carboxamide

tetrahydrofurane-2-carboximidate de methyle

Refernces