Technology Process of C20H19N3O5
There total 4 articles about C20H19N3O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-(3,4-dimethoxybenzamido)acetic acid;
With
1-chloro-1-(dimethylamino)-2-methyl-1-propene;
In
dichloromethane;
at 0 - 20 ℃;
for 0.5h;
Inert atmosphere;
3-aminoisoquinolin-1(2H)-one;
With
pyridine;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
for 10h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 10 h / 25 °C
2.1: potassium hydroxide; water / ethanol / 2 h / 70 °C
3.1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / dichloromethane / 0.5 h / 0 - 20 °C / Inert atmosphere
3.2: 10 h / 20 °C
With
1-chloro-1-(dimethylamino)-2-methyl-1-propene; water; N-ethyl-N,N-diisopropylamine; HATU; potassium hydroxide;
In
ethanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium hydroxide; water / ethanol / 2 h / 70 °C
2.1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / dichloromethane / 0.5 h / 0 - 20 °C / Inert atmosphere
2.2: 10 h / 20 °C
With
1-chloro-1-(dimethylamino)-2-methyl-1-propene; water; potassium hydroxide;
In
ethanol; dichloromethane;