3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine

Base Information

• Chemical Name: 3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine
• CAS No.: 5657-64-7
• Molecular Formula: C6H4 N2 O2
• Molecular Weight: 136.11
• Hs Code.: 2933399090
• Mol file: 5657-64-7.mol

Synonyms:Nicotinonitrile,1,2-dihydro-4-hydroxy-2-oxo- (7CI); Nicotinonitrile, 2,4-dihydroxy- (8CI); NSC409910; Norricinine

Chemical Property of 3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine

Chemical Property:

• Vapor Pressure: 0.00266mmHg at 25°C
• Boiling Point: 254.3°Cat760mmHg
• PKA: 4.50±1.00(Predicted)
• Flash Point: 107.6°C
• PSA: 76.88000
• Density: 1.47g/cm³
• LogP: -0.04782
• Storage Temp.: 2-8°C

Purity/Quality:

99%min ^*data from raw suppliers

3-Cyano-2,4-dihydroxypyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine

There total 1 articles about 3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chloro-2,4-dihydroxy-nicotinonitrile (19867-18-6) → 2,4-dihydroxy-nicotinonitrile (5657-64-7)

Guidance literature:

With sulfuric acid; zinc;

Reference yield:

2,4-dihydroxy-nicotinonitrile (5657-64-7) → 3-deazauracil (626-03-9,84719-31-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄ / Behandeln des Reaktionsgemisches mit wss. NaNO₂

2: concentrated aqueous hydrochloric acid

With hydrogenchloride; sulfuric acid;

upstream raw materials:

6-chloro-2,4-dihydroxy-nicotinonitrile

Downstream raw materials:

3-deazauracil