L-1-Cbz-pipecolinamide

Base Information

• Chemical Name: L-1-Cbz-pipecolinamide
• CAS No.: 61703-39-7
• Molecular Formula: C14H18N2O3
• Molecular Weight: 262.309
• Hs Code.: 2933399090
• Mol file: 61703-39-7.mol

Synonyms:Benzyl(2S)-2-(aminocarbonyl)piperidine-1-carboxylate;1-Piperidinecarboxylicacid, 2-(aminocarbonyl)-, phenylmethyl ester, (S)- (9CI);

Chemical Property of L-1-Cbz-pipecolinamide

Chemical Property:

• Vapor Pressure: 3.3E-09mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 475.5 °C at 760 mmHg
• Flash Point: 241.4 °C
• PSA: 72.63000
• Density: 1.224 g/cm³
• LogP: 2.30120
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

L-1-CBZ-pipecolinamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-1-Cbz-pipecolinamide

There total 1 articles about L-1-Cbz-pipecolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-(carbobenzyloxy)-2-piperidinecarboxylic acid (28697-11-2) → benzyl (2S)-2-(aminocarbonyl)piperidine-1-carboxylate (61703-39-7)

Guidance literature:

(S)-1-(carbobenzyloxy)-2-piperidinecarboxylic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

With ammonia; In 1,4-dioxane; N,N-dimethyl-formamide; for 2h;

Reference yield:

benzyl (2S)-2-(aminocarbonyl)piperidine-1-carboxylate (61703-39-7) → benzyl (2S)-2-(aminomethyl)piperidine-1-carboxylate (1154871-02-9,811842-18-9)

Guidance literature:

benzyl (2S)-2-(aminocarbonyl)piperidine-1-carboxylate; With borane-THF; In tetrahydrofuran; for 24h;

With water; In tetrahydrofuran;

With trifluoroacetic acid; In water; pH=3;

upstream raw materials:

(S)-1-(carbobenzyloxy)-2-piperidinecarboxylic acid

Downstream raw materials:

benzyl (2S)-2-(aminomethyl)piperidine-1-carboxylate

Refernces