2-PROPENOIC ACID, 3-(3-FURANYL)-, ETHYL ESTER

Base Information

• Chemical Name: 2-PROPENOIC ACID, 3-(3-FURANYL)-, ETHYL ESTER
• CAS No.: 58963-70-5
• Molecular Formula: C9H10 O3
• Molecular Weight: 166.177
• Mol file: 58963-70-5.mol

Synonyms:Ethyl3-furan-3-ylacrylate

Chemical Property of 2-PROPENOIC ACID, 3-(3-FURANYL)-, ETHYL ESTER

Chemical Property:

• PSA: 39.44000
• LogP: 1.85590

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-3-(FURAN-3-YL)ACRYLATE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-PROPENOIC ACID, 3-(3-FURANYL)-, ETHYL ESTER

There total 15 articles about 2-PROPENOIC ACID, 3-(3-FURANYL)-, ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

furan-3-carboxaldehyde (498-60-2) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → (E)-3-Furan-3-yl-acrylic acid ethyl ester (58963-70-5)

Guidance literature:

In benzene; Heating;

DOI:10.1039/cc9960001357

Reference yield: 99.0%

furan-3-carboxaldehyde (498-60-2) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → trans-3-furan-3-yl-acrylic acid ethyl ester (58963-70-5)

Guidance literature:

In tetrahydrofuran; for 2h; Heating / reflux;

Reference yield: 92.0%

furan-3-carboxaldehyde (498-60-2) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → trans-3-furan-3-yl-acrylic acid ethyl ester (58963-70-5) + (Z)-3-furan-3-yl-acrylic acid ethyl ester

Guidance literature:

In toluene; for 2h; Heating;

DOI:10.1002/chem.200501034

upstream raw materials:

furan-3-carboxaldehyde

ethyl (triphenylphosphoranylidene)acetate

furan-3-methanol

diethoxyphosphoryl-acetic acid ethyl ester

Downstream raw materials:

(E)-3-furan-3-yl-acrylic acid

3-(furan-3-yl)prop-2-enoic acid

(E)-phenyl 3-(furan-3-yl)acrylate

(E)-3-(furan-3-yl)propenal

Refernces

• 1、 Crimmins,Jung,Gray. "Synthetic studies on the ginkgolides: Total synthesis of (±)-bilobalide". . p. 3146 - 3155. Retrieved 1993.
• 2、 -. "Preparation method of (E)-3-(3-furyl) acrylic acid". Paragraph 0092-0094. . Retrieved 2020/08/30.
• 3、 Bober, Ashley E.,Proto, Justin T.,Brummond, Kay M.. "Intramolecular Didehydro-Diels-Alder Reaction for the Synthesis of Benzo- and Dihydrobenzo-Fused Heterocycles". supporting information. p. 1500 - 1503. Retrieved 2017/04/13.