2-(o-formylphenoxy)hexylamide

Base Information

• Chemical Name: 2-(o-formylphenoxy)hexylamide
• CAS No.: 158745-56-3
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.283
• Mol file: 158745-56-3.mol

Synonyms:2-(o-formylphenoxy)hexylamide

Chemical Property of 2-(o-formylphenoxy)hexylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(o-formylphenoxy)hexylamide

There total 4 articles about 2-(o-formylphenoxy)hexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

methyl 2-(2-formylphenoxy)hexanoate (138320-26-0) → 2-(o-formylphenoxy)hexylamide (158745-56-3)

Guidance literature:

With ammonia; In ethanol; for 72h; Ambient temperature;

Reference yield:

methyl 2-bromohexanoate (5445-19-2) → 2-(o-formylphenoxy)hexylamide (158745-56-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / potassium carbonate / dimethylformamide / 4 h / Heating

2: 80 percent / NH₃ / ethanol / 72 h / Ambient temperature

With ammonia; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

Reference yield:

salicylaldehyde (90-02-8) → 2-(o-formylphenoxy)hexylamide (158745-56-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / potassium carbonate / dimethylformamide / 4 h / Heating

2: 80 percent / NH₃ / ethanol / 72 h / Ambient temperature

With ammonia; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

upstream raw materials:

methyl 2-(2-formylphenoxy)hexanoate

methyl 2-bromohexanoate

salicylaldehyde

Downstream raw materials:

2-(o-carboxyphenoxy)hexylamide

Refernces

• 1、 Kwiecien, H.. "Synthesis of 2-Phenoxyhexanal and 2-(o-Formylphenoxy)Hexanoic Acid and Its Derivatives". . p. 661 - 666. Retrieved 2007/10/02.