cyanoacetate

Base Information

• Chemical Name: cyanoacetate
• CAS No.: 23297-32-7
• Molecular Formula: C₃H₂NO₂
• Molecular Weight: 84.0544
• Mol file: 23297-32-7.mol

Synonyms:cyanoacetate

Chemical Property of cyanoacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyanoacetate

There total 6 articles about cyanoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-α-cyanocinnamic acid (14378-06-4) → cyanoacetate (23297-32-7) + benzaldehyde (100-52-7)

Guidance literature:

With potassium hydroxide; potassium chloride; In water; acetonitrile; at 30 ℃; Rate constant; Mechanism; Thermodynamic data; pH 10.85-13.64, ΔH(excit.), ΔS(excit.);

DOI:10.1021/ja00370a033

Reference yield:

2-cyano-3-(p-methylphenyl)propenoic acid (20374-48-5) → cyanoacetate (23297-32-7) + 4-methyl-benzaldehyde (104-87-0)

Guidance literature:

With potassium hydroxide; potassium chloride; In water; acetonitrile; at 30 ℃; Rate constant; Mechanism; Thermodynamic data; pH 11.68-13.63, ΔH(excit.), ΔS(excit.);

DOI:10.1021/ja00370a033

Reference yield:

2-cyano-3-(p-chlorophenyl)propenoic acid (20374-46-3) → cyanoacetate (23297-32-7) + 4-chlorobenzaldehyde (104-88-1)

Guidance literature:

With potassium hydroxide; potassium chloride; In water; acetonitrile; at 30 ℃; Rate constant; Mechanism; Thermodynamic data; pH 10.74-13.58, ΔH(excit.), ΔS(excit.);

DOI:10.1021/ja00370a033

upstream raw materials:

(E)-2-cyano-3-(4-methoxyphenyl)acrylic acid

2-cyano-3-(p-chlorophenyl)propenoic acid

(E)-α-cyanocinnamic acid

2-cyano-3-(p-methylphenyl)propenoic acid

Downstream raw materials:

N,N'-dimethylbenzylamine

cyanoacetic acid

Refernces

• 1、 Inoue, Masashi,Bruice, Thomas C.. "Extended E1cB Mechanism for Ester Hydrolysis: Allylic Substitution via Carbanion in Ester Hydrolysis". . p. 1644 - 1653. Retrieved 2007/10/02.