PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE

Base Information

• Chemical Name: PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE
• CAS No.: 106966-25-0
• Molecular Formula: C7H17N2O2.Br
• Molecular Weight: 110.16
• Mol file: 106966-25-0.mol

Synonyms:Propanoic acid, 3-(2,2,2-trimethylhydrazinyl)-, methyl ester bromide

Chemical Property of PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE

Chemical Property:

• Vapor Pressure: 5hPa at 20-25℃
• PSA: 38.33000
• Density: 1.38 at 20℃
• LogP: -2.84480

Purity/Quality:

99% ^*data from raw suppliers

3-(2,2,2-TRIMETHYLHYDRAZINYL)-PROPANOIC ACID METHYL ESTER BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-(2,2,2-Trimethylhydrazine)methylpropionate bromide can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Technology Process of PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE

There total 1 articles about PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.3%

methyl bromide (74-83-9) + 1,1-dimethyl-2-(2-methoxycarbonylethyl)hydrazine (4753-43-9) → 3-(2,2,2-trimethylhydrazinium)propionic acid methyl ester bromide (106966-25-0)

Guidance literature:

In ethanol; at 0 ℃; for 1.5h;

Reference yield:

3-(2,2,2-trimethylhydrazinium)propionic acid methyl ester bromide (106966-25-0) → meldonium (76144-81-5)

Guidance literature:

3-(2,2,2-trimethylhydrazinium)propionic acid methyl ester bromide; With potassium hydroxide; ethanol; at 18 - 20 ℃; for 0.0833333 - 0.166667h;

With carbon dioxide; at 2 - 4 ℃; pH=8.1 - 8.5; Product distribution / selectivity;

upstream raw materials:

methyl bromide

1,1-dimethyl-2-(2-methoxycarbonylethyl)hydrazine

Downstream raw materials:

meldonium

Refernces