4-Methoxyphenyl boronic acid anhydride

Base Information

• Chemical Name: 4-Methoxyphenyl boronic acid anhydride
• CAS No.: 7294-51-1
• Molecular Formula: C21H21 B3 O6
• Molecular Weight: 401.827
• Hs Code.: 2931900090
• Mol file: 7294-51-1.mol

Synonyms:Boroxin,tris(4-methoxyphenyl)- (9CI); Boroxin, tris(p-methoxyphenyl)- (6CI,7CI,8CI);2,4,6-Tris(4-methoxyphenyl)boroxin; Tris(4-methoxyphenyl)boroxin

Chemical Property of 4-Methoxyphenyl boronic acid anhydride

Chemical Property:

• Melting Point: 209 - 211 °C (hexane)
• PSA: 55.38000
• LogP: 1.26180

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Methoxyphenyl boronic acid anhydride

There total 14 articles about 4-Methoxyphenyl boronic acid anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

hydrogenchloride (7647-01-0,15364-23-5) + Pt(OB(C6H4OMe-4)OB(C6H4OMe-4)O)(dppe) (883153-46-6) → [platinum(II)dichloride(1,2-bis(diphenylphosphino)ethane)] (83095-83-4,14647-25-7) + 2,4,6-tris(4-methoxyphenyl)boroxine (7294-51-1) + 4-methoxyphenylboronic acid (5720-07-0)

Guidance literature:

In tetrahydrofuran; under N2 or Ar; to a THF soln. of Pt-contg. compd. (0.05 mmol) was addedHCl (0.1 mmol); stirring at room temp. for 2 h; addn. of hexane; the complex was filtered off and dried under vac.; elem. anal.;

DOI:10.1021/om0509903

Reference yield: 91.0%

Pt(OB(C6H4OMe-4)OB(C6H4OMe-4)O)(dppe) (883153-46-6) + trifluoroacetic acid (76-05-1) → Pt(CF3CO2)2(dppe) (69005-06-7) + 2,4,6-tris(4-methoxyphenyl)boroxine (7294-51-1) + 4-methoxyphenylboronic acid (5720-07-0)

Guidance literature:

In tetrahydrofuran; under N2 or Ar; to a THF soln. of Pt-contg. compd. (0.05 mmol) was addedCF3COOH (0.1 mmol); stirring at room temp. for 2 h; addn. of hexane; the complex was filtered off and dried under vac.; elem. anal.;

DOI:10.1021/om0509903

Reference yield: 59.0%

1-bromo-4-methoxy-benzene (104-92-7) + triethyl borate (150-46-9) → 2,4,6-tris(4-methoxyphenyl)boroxine (7294-51-1)

Guidance literature:

1-bromo-4-methoxy-benzene; With magnesium; In tetrahydrofuran; Inert atmosphere;

triethyl borate; In tetrahydrofuran; hexane; at -60 - 0 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/op025615q

upstream raw materials:

4-methoxyphenylboronic acid

1-bromo-4-methoxy-benzene

4-methoxyphenyl-N,N-diisopropylaminoborane

4-bromo-phenol

Downstream raw materials:

2-(4-methoxyphenyl)-1,3,6,2-dioxazaborocane

4-CH₃OC₆H₄B(O-n-C₄H₉)2

1-fluoro-4-methoxybenzene

3-(4-methoxyphenyl)cyclohexanone

Refernces

• 1、 Wu, Chunlin,Qin, Xurong,Moeljadi, Adhitya Mangala Putra,Hirao, Hajime,Zhou, Jianrong Steve. "Copper-Catalyzed Asymmetric Arylation of N-Heteroaryl Aldimines: Elementary Step of a 1,4-Insertion". supporting information. p. 2705 - 2709. Retrieved 2019/02/06.
• 2、 Bartholomeyzik, Teresa,Pendrill, Robert,Lihammar, Richard,Jiang, Tuo,Widmalm, G?ran,B?ckvall, Jan-E.. "Kinetics and Mechanism of the Palladium-Catalyzed Oxidative Arylating Carbocyclization of Allenynes". supporting information. p. 298 - 309. Retrieved 2018/01/17.