1,3-Bis(4-bromophenyl)propanone

Base Information

• Chemical Name: 1,3-Bis(4-bromophenyl)propanone
• CAS No.: 54523-47-6
• Molecular Formula: C15H12Br2O
• Molecular Weight: 368.068
• Hs Code.: 2914700090
• Mol file: 54523-47-6.mol

Synonyms:4,4'-Dibromodibenzyl ketone;1,3-Bis(4-bromophenyl)acetone;1,3-Bis(p-bromophenyl)-2-propanone;AG-F-89414;

Chemical Property of 1,3-Bis(4-bromophenyl)propanone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 117.0 to 121.0 °C
• Refractive Index: 1.619
• Boiling Point: 427.298 °C at 760 mmHg
• Flash Point: 113.805 °C
• PSA: 17.07000
• Density: 1.608 g/cm³
• LogP: 4.56590

Purity/Quality:

99% ^*data from raw suppliers

1,3-Bis(4-bromophenyl)-2-propanone >99.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Bis(4-bromophenyl)propanone

There total 15 articles about 1,3-Bis(4-bromophenyl)propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-(4-bromophenyl)-acetic acid (1878-68-8) → 1,3-bis(4-bromophenyl)propan-2-one (54523-47-6)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1134/S0012500812020024

Reference yield: 82.0%

Ethyl 4-bromophenylacetate (14062-25-0) → 1,3-bis(4-bromophenyl)propan-2-one (54523-47-6)

Guidance literature:

With sodium hydride; In toluene; at 30 - 78 ℃;

Reference yield: 76.7%

1-bromomethyl-4-bromobenzene (589-15-1) → 1,3-bis(4-bromophenyl)propan-2-one (54523-47-6)

Guidance literature:

In various solvent(s); at 0 - 50 ℃;

DOI:10.1021/ol0629770

upstream raw materials:

Ethyl 4-bromophenylacetate

(4-bromo-phenyl)-acetic acid methyl ester

Ethyl oxalyl chloride

1-bromomethyl-4-bromobenzene

Downstream raw materials:

4,7-bis(4-bromophenyl)-5,6-diphenylisoindoline-1,3-dione

7,11-bis(4-bromophenyl)-8H-acenaphtho[1,2-f]isoindole-8,10(9H)-dione

2,3,5-tris(4-bromophenyl)-4-phenylcyclopenta-2,4-dienone

Refernces

• 1、 Athukorale, Sumudu,Borrego, Ernesto I.,Donnadieu, Bruno,Farajidizaji, Behzad,Jazi, Mehdi,Pittman, Charles U.,Smith, Dennis W.. "Triphenylene-Enchained Perfluorocyclobutyl Aryl Ether Polymers: A Modular Synthetic Route to Processable Thermoplastics Approaching Upper Limit Tgand Photostability". . p. 7666 - 7672. Retrieved 2021/09/02.
• 2、 Liu, Yan,Peng, Xian,Peng, Yungui,She, Rui,Zhou, Xin. "Catalytic Asymmetric (3 + 3) Cycloaddition of Oxyallyl Zwitterions with α-Diazomethylphosphonates". supporting information. p. 7295 - 7300. Retrieved 2021/10/01.