3,4,5-TRIPHENYL-1,2,4-TRIAZOLE

Base Information

• Chemical Name: 3,4,5-TRIPHENYL-1,2,4-TRIAZOLE
• CAS No.: 4073-72-7
• Molecular Formula: C20H15N3
• Molecular Weight: 297.359
• Hs Code.: 2933990090
• Mol file: 4073-72-7.mol

Synonyms:3,4,5-Triphenyl-1,2,4-triazole;

Chemical Property of 3,4,5-TRIPHENYL-1,2,4-TRIAZOLE

Chemical Property:

• Boiling Point: 508 °C at 760 mmHg
• Flash Point: 261 °C
• PSA: 30.71000
• Density: 1.14 g/cm³
• LogP: 4.60130
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

3,4,5-Triphenyl-4H-1,2,4-triazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4,5-TRIPHENYL-1,2,4-TRIAZOLE

There total 26 articles about 3,4,5-TRIPHENYL-1,2,4-TRIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

benzaldehyde (100-52-7) + N-phenylbenzamidrazone (2038-98-4) → 3,4,5-triphenyl-1,2,4-triazole (4073-72-7)

Guidance literature:

With ammonium cerium (IV) nitrate; at 80 ℃; for 1h; Time; Reagent/catalyst;

DOI:10.1055/s-0034-1378909

Reference yield: 91.0%

iodobenzene (591-50-4) + N-phenylbenzamidrazone (2038-98-4) + molybdenum hexacarbonyl (13939-06-5,199620-15-0) → 3,4,5-triphenyl-1,2,4-triazole (4073-72-7)

Guidance literature:

With tributyl-amine; tetraethylammonium chloride; In N,N-dimethyl-formamide; at 150 ℃; for 10h; Reagent/catalyst; Solvent; Time; Inert atmosphere;

DOI:10.1002/adsc.201500703

Reference yield: 88.0%

iodobenzene (591-50-4) + 3,4-diphenyl-1,2,4-triazole (14331-64-7) → 3,4,5-triphenyl-1,2,4-triazole (4073-72-7)

Guidance literature:

With copper; potassium carbonate; at 120 ℃; for 12h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.12.064

upstream raw materials:

4-(o-carboxyphenyl)-3,5-diphenyl(1,2,4) triazole

thiosemicarbazide

N-phenyl-benzimidoyl chloride

N-phenyl benzoyl amide

Downstream raw materials:

3-(4-bromophenyl)-4,5-diphenyl-4H-1,2,4-triazole

Refernces

• 1、 Nakka, Mangarao,Tadikonda, Ramu,Nakka, Srinivas,Vidavalur, Siddaiah. "Synthesis of 1,2,4-Triazoles, N-Fused 1,2,4-Triazoles and 1,2,4-Oxadiazoles via Molybdenum Hexacarbonyl-Mediated Carbonylation of Aryl Iodides". supporting information. p. 520 - 525. Retrieved 2016/02/27.
• 2、 Nakka, Mangarao,Tadikonda, Ramu,Rayavarapu, Srinuvasarao,Sarakula, Prasanthi,Vidavalur, Siddaiah. "A simple and efficient synthesis of 3,4,5-trisubstituted/N-fused 1,2,4-triazoles via ceric ammonium nitrate catalyzed oxidative cyclization of amidrazones with aldehydes using polyethylene glycol as a recyclable reaction medium". . p. 517 - 525. Retrieved 2015/02/19.