1-Bromo-2,4-dichloro-5-fluorobenzene

Base Information

• Chemical Name: 1-Bromo-2,4-dichloro-5-fluorobenzene
• CAS No.: 1481-63-6
• Molecular Formula: C6H2BrCl2F
• Molecular Weight: 243.89
• DSSTox Substance ID: DTXSID90472914
• Wikidata: Q82302105
• Mol file: 1481-63-6.mol

Synonyms:1-Bromo-2,4-dichloro-5-fluorobenzene;1481-63-6;2,4-Dichloro-5-fluorobromobenzene;5-bromo-2,4-dichlorofluorobenzene;Benzene, 1-bromo-2,4-dichloro-5-fluoro-;MFCD06659468;Benzene,1-bromo-2,4-dichloro-5-fluoro-;SCHEMBL8458346;DTXSID90472914;HNCWLJLWAVCZDM-UHFFFAOYSA-N;AKOS015911894;FS-5444;SY022871;2 pound not4-Dichloro-5-fluorobromobenzene;CS-0036607;FT-0607442;A856832;1,2,3,4,5-Pentachloro-5-(2-ethylhexyl)cyclopentadiene;1-bromo-2,4-dichloro-5-fluorobenzene

Chemical Property of 1-Bromo-2,4-dichloro-5-fluorobenzene

Chemical Property:

• Vapor Pressure: 0.068mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 237.756 °C at 760 mmHg
• Flash Point: 97.592 °C
• PSA: 0.00000
• Density: 1.824 g/cm³
• LogP: 3.89500
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 241.87010
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-2,4-dichloro-5-fluorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Br)Cl)Cl)F

Technology Process of 1-Bromo-2,4-dichloro-5-fluorobenzene

There total 2 articles about 1-Bromo-2,4-dichloro-5-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-dichloro-4-fluorobenzene (1435-48-9) → 1-bromo-2,4-dichloro-5-fluorobenzene (1481-63-6)

Guidance literature:

With bromine; iron;

Reference yield:

2,4-dichloro-5-fluoroaniline (348-64-1) → 1-bromo-2,4-dichloro-5-fluorobenzene (1481-63-6)

Guidance literature:

Multistep reaction; (i) NaNO₂, aq. H₂SO₄, (ii) CuBr;

Reference yield: 86.0%

bis(phenylphosphino)ethane + acrylic acid n-butyl ester (141-32-2,9003-49-0) + 1-bromo-2,4-dichloro-5-fluorobenzene (1481-63-6) → butyl 2,4-dichloro-5-fluorocinnamate

Guidance literature:

With sodium acetate; triphenylphosphine; palladium diacetate; In dichloromethane; ISOPROPYLAMIDE; water;

upstream raw materials:

2,4-dichloro-5-fluoroaniline

1,3-dichloro-4-fluorobenzene

Downstream raw materials:

1,2,4-trichloro-5-fluoro-benzene

2,4-dichloro-5-fluoroacetophenone

1-Fluor-3,6-dibrom-2,4,5-trifluorbenzol

2,4-dichloro-5-fluoro-benzonitrile