3-Bromo-2-nitroaniline

Base Information

• Chemical Name: 3-Bromo-2-nitroaniline
• CAS No.: 7138-15-0
• Molecular Formula: C6H5BrN2O2
• Molecular Weight: 217.022
• Hs Code.: 29214200
• Mol file: 7138-15-0.mol

Synonyms:benzenamine, 3-bromo-2-nitro-;

Chemical Property of 3-Bromo-2-nitroaniline

Chemical Property:

• Vapor Pressure: 0.00127mmHg at 25°C
• Melting Point: 118 °C
• Refractive Index: 1.669
• Boiling Point: 298.4 °C at 760 mmHg
• PKA: -1.30±0.10(Predicted)
• Flash Point: 134.3 °C
• PSA: 71.84000
• Density: 1.812 g/cm³
• LogP: 3.04390
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

3-Bromo-2-nitroaniline ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 9-26-36/37-60

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Bromo-2-nitroaniline

There total 2 articles about 3-Bromo-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-1,2-dinitrobenzene (610-38-8) + ammonia (7664-41-7) + furan-2,3,5(4H)-trione pyridine (1:1) → 4-bromo-2-nitrophenol (7693-52-9) + 5-bromo-2-nitrophenol (27684-84-0) + 3-bromo-2-nitrophenylamine (7138-15-0)

Guidance literature:

Reference yield:

→ 3-bromo-2-nitrophenylamine (7138-15-0)

Guidance literature:

1-Brom-3-hydroxylamino-2-nitro-benzol, Saeure/Δ (neben 3,3'-Dibrom-2,2'-dinitro-azoxybenzol);

Reference yield: 92.0%

3-bromo-2-nitrophenylamine (7138-15-0) + 2-tri-n-butylstannylpyridine (17997-47-6) → 2-nitro-3-(pyridine-2-yl)aniline

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; for 6h; Reflux;

DOI:10.1002/chem.202003271

upstream raw materials:

4-bromo-1,2-dinitrobenzene

ammonia

Downstream raw materials:

3-(methylsulfonyl)-2-nitroaniline

N-(2-amino-3-bromophenyl)-2-chloropropionamide

6-bromo-1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline

4-bromo-1H-benzo[d]imidazole