AC-DEVD-PNA

Base Information

• Chemical Name: AC-DEVD-PNA
• CAS No.: 189950-66-1
• Molecular Formula: C26H34N6O13
• Molecular Weight: 638.58
• Mol file: 189950-66-1.mol

Synonyms:Acetyl-aspartyl-glutamyl-valyl-aspartic Acid P-nitroanilide;

Chemical Property of AC-DEVD-PNA

Chemical Property:

• Appearance/Colour: white
• Boiling Point: 1191.1±65.0 °C(Predicted)
• PKA: 2.97±0.10(Predicted)
• PSA: 303.22000
• Density: 1.448±0.06 g/cm3(Predicted)
• LogP: 1.12240
• Storage Temp.: −20°C
• Water Solubility.: Soluble in water (partly), dimethyl sulfoxide, buffer, pH 7, and acetonitrile:methanol (1:1) (1 mg/ml).

Purity/Quality:

99% ^*data from raw suppliers

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide ≥97% (HPLC), powder ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase. N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide is an chromogenic substrate for Caspase 3 and CCP-32. N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.