2,6-dichlorobenzenesulfonyl chloride

Base Information

• Chemical Name: 2,6-dichlorobenzenesulfonyl chloride
• CAS No.: 6579-54-0
• Molecular Formula: C6H3Cl3O2S
• Molecular Weight: 245.514
• Hs Code.: 29049090
• Mol file: 6579-54-0.mol

Synonyms:2,6-Dichlorobenzenesulphonyl chloride;2,6-Dichlorobenzene-1-sulfonyl chloride;Benzenesulfonyl chloride, 2,6-dichloro-;

Chemical Property of 2,6-dichlorobenzenesulfonyl chloride

Chemical Property:

• Vapor Pressure: 0.000423mmHg at 25°C
• Melting Point: 53-56 °C(lit.)
• Refractive Index: 1.581
• Boiling Point: 326 °C at 760 mmHg
• Flash Point: 150.9 °C
• PSA: 42.52000
• Density: 1.636 g/cm³
• LogP: 4.00170
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Moisture Sensitive
• Water Solubility.: Reacts with water.

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dichlorobenzenesulfonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,6-Dichlorobenzenesulfonyl chloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of 2,6-dichlorobenzenesulfonyl chloride

There total 3 articles about 2,6-dichlorobenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2,6-dichlorothiophenol (24966-39-0) → 2,6-dichlorobenzenesulfonyl chloride (6579-54-0)

Guidance literature:

With N-chloro-succinimide; potassium acetate; In dichloromethane;

Reference yield:

sulfur dioxide (7446-09-5,12143-17-8,89125-89-3) + 2,6-Dichloroaniline (608-31-1) → 2,6-dichlorobenzenesulfonyl chloride (6579-54-0)

Guidance literature:

With hydrogenchloride; acetic acid; sodium nitrite; In water; toluene; Petroleum ether;

Reference yield:

→ 2,6-dichlorobenzenesulfonyl chloride (6579-54-0)

Guidance literature:

Aus 2.6-Dichlor-anilin in Eg. mit konz. HCl (0grad), dann wss. NaNO2 (0grad, 30 min),dann Eintragen der Diazo-Lsg. in ges. Lsg. von SO2 in Eg (20grad, 1h);

upstream raw materials:

2,6-dichlorothiophenol

sulfur dioxide

2,6-Dichloroaniline

Downstream raw materials:

2-(2,6-dichloro-benzenesulfonyl)-2-aza-bicyclo[2.2.2]octane-3-carboxylic acid ethyl ester

2,6-Dichloro-N-[4-(3-chloro-thien-2-yl)-1,3-thiazol-2-yl]benzenesulfonamide

2,6-dichloro-3-nitrobenzenesulfonic acid

potassium 2,6-dichlorophenylsulfonamidomethyltrifluoroborate

Refernces

• 1、 -. "Il-8 receptor antagonists". . . Retrieved 2008/06/13.
• 2、 -. "Il-8 receptor antagonists". . . Retrieved 2008/06/13.