cyclohexyl-malonic acid di-tert-butyl ester

Base Information

• Chemical Name: cyclohexyl-malonic acid di-tert-butyl ester
• CAS No.: 854707-20-3
• Molecular Formula: C₁₇H₃₀O₄
• Molecular Weight: 298.423
• Mol file: 854707-20-3.mol

Synonyms:cyclohexyl-malonic acid di-tert-butyl ester

Chemical Property of cyclohexyl-malonic acid di-tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexyl-malonic acid di-tert-butyl ester

There total 1 articles about cyclohexyl-malonic acid di-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromocyclohexane (108-85-0) → cyclohexyl-malonic acid di-tert-butyl ester (854707-20-3)

Guidance literature:

With tert-butyl alcohol;

DOI:10.1021/ja01123a506

Reference yield:

cyclohexyl-malonic acid di-tert-butyl ester (854707-20-3) + benzoyl chloride (98-88-4) → 2-cyclohexyl-1-phenylethan-1-one (5653-09-8)

Guidance literature:

With sodium hydride;

DOI:10.1021/ja01123a506

Reference yield:

cyclohexyl-malonic acid di-tert-butyl ester (854707-20-3) → 2-cyclohexyl-1-(o-tolyl)ethanone

Guidance literature:

With sodium hydride; anschliessend Erwaermen mit o-Toluoylchlorid in Benzol und Erhitzen des Reaktionsprodukts mit Toluol-4-sulfonsaeure und Acetanhydrid in Essigsaeure;

DOI:10.1021/ja01123a506

upstream raw materials:

1-bromocyclohexane

Downstream raw materials:

2-cyclohexyl-1-phenylethan-1-one