CIS-1,3-DIACETOXYCYCLOHEXANE

Base Information

• Chemical Name: CIS-1,3-DIACETOXYCYCLOHEXANE
• CAS No.: 832-09-7
• Molecular Formula: C10H16 O4
• Molecular Weight: 200.23
• Mol file: 832-09-7.mol

Synonyms:1,3-Cyclohexanediol,diacetate, cis- (8CI)

Chemical Property of CIS-1,3-DIACETOXYCYCLOHEXANE

Chemical Property:

Purity/Quality:

98%Min ^*data from raw suppliers

CIS-1,3-DIACETOXYCYCLOHEXANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CIS-1,3-DIACETOXYCYCLOHEXANE

There total 22 articles about CIS-1,3-DIACETOXYCYCLOHEXANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

acetic anhydride (108-24-7) + C18H19OP → (1R*,3S*)-1,3-cyclohexanediol diacetate (832-09-7) + trans-1,3-diacetoxycyclohexane (832-09-7,6939-74-8,26688-53-9,116565-28-7,140237-33-8,140434-51-1,140434-52-2)

Guidance literature:

With sodium hydroperoxide; Wilkinson's catalyst;

DOI:10.1021/ja00228a068

Reference yield: 82.0%

acetic anhydride (108-24-7) + C18H19OP → (1R*,3S*)-1,3-cyclohexanediol diacetate (832-09-7) + trans-1,3-diacetoxycyclohexane (832-09-7,6939-74-8,26688-53-9,116565-28-7,140237-33-8,140434-51-1,140434-52-2)

Guidance literature:

With sodium hydroperoxide; Wilkinson's catalyst;

DOI:10.1021/ja00228a068

Reference yield:

Isopropenyl acetate (108-22-5) + cyclohexane-1,3-diol (504-01-8) → (1R*,3S*)-1,3-cyclohexanediol diacetate (832-09-7) + Di-O-acetyl-trans-cyclohexandiol-(1,3) (888027-80-3)

Guidance literature:

With Candida antarctica lipase B; dicarbonyl(chloro)(η⁵-pentaphenylcyclopentadienyl)ruthenium(II); sodium carbonate; potassium tert-butylate; In toluene; at 25 ℃; for 24h; Title compound not separated from byproducts;

DOI:10.1021/jo060002n

upstream raw materials:

cis-1,3-cyclohexanediol

acetic anhydride

(1R,3r,5S)-bicyclo[3.1.0]hexan-3-ol

mercury(II) diacetate

Refernces

• 1、 Evans, David A.,Fu, Gregory C.,Hoveyda, Amir H.. "Rhodium(I)- and iridium(I)-catalyzed hydroboration reactions: Scope and synthetic applications". . p. 6671 - 6679. Retrieved 2007/10/02.