Technology Process of 6-Ethoxy-7-Methoxyquinazoline-4-One
There total 6 articles about 6-Ethoxy-7-Methoxyquinazoline-4-One which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
6-hydroxy-7-methoxyquinazolin-4(3H)-one;
With
caesium carbonate;
In
methanol; water; acetonitrile;
at 25 ℃;
for 0.5h;
ethyl iodide;
In
methanol; water; acetonitrile;
at 25 - 60 ℃;
for 40h;
- Guidance literature:
-
6-hydroxy-7-methoxyquinazolin-4(3H)-one;
With
caesium carbonate;
In
methanol; water; acetonitrile;
at 20 ℃;
for 0.5h;
ethyl bromide;
In
methanol; water; acetonitrile;
at 60 ℃;
for 48h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 90 - 95 °C
2: methanol; sodium dithionite; water / 55 °C
3: acetic acid / 130 °C
With
methanol; sodium dithionite; water; potassium carbonate; acetic acid; potassium iodide;
In
N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.07.019