Bis(4-methoxyphenyl) sulfide

Base Information

• Chemical Name: Bis(4-methoxyphenyl) sulfide
• CAS No.: 3393-77-9
• Molecular Formula: C14H14 O2 S
• Molecular Weight: 246.33
• European Community (EC) Number: 608-921-5
• DSSTox Substance ID: DTXSID10347195
• Nikkaji Number: J283.967I
• Wikidata: Q72508714
• Mol file: 3393-77-9.mol

Synonyms:3393-77-9;4,4'-Dimethoxy diphenyl sulfide;Bis(4-methoxyphenyl) sulfide;1-methoxy-4-(4-methoxyphenyl)sulfanylbenzene;Benzene, 1,1'-thiobis[4-methoxy-;bis(4-methoxyphenyl)sulfane;Bis-[p-methoxyphenyl]-sulfid;SCHEMBL482369;DTXSID10347195;MFCD00068752;AKOS015898796;AS-13449;1-methoxy-4-[(4-methoxyphenyl)thio]benzene;FT-0600306;1-methoxy-4-(4-methoxyphenyl)sulfanyl-benzene;E87020;1-Methoxy-4-[(4-methoxyphenyl)sulfanyl]benzene;1-Methoxy-4-[(4-methoxyphenyl)sulfanyl]benzene #;A822008;J-519879

Chemical Property of Bis(4-methoxyphenyl) sulfide

Chemical Property:

• Melting Point: 43-44 °C
• Boiling Point: 396.9°Cat760mmHg
• Flash Point: 193.9°C
• PSA: 43.76000
• Density: 1.17
• LogP: 3.85500
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 246.07145086
• Heavy Atom Count: 17
• Complexity: 184

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4''-DimethoxyDiphenylSulfide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)SC2=CC=C(C=C2)OC

Technology Process of Bis(4-methoxyphenyl) sulfide

There total 71 articles about Bis(4-methoxyphenyl) sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-Methoxybenzenethiol (696-63-9) + para-iodoanisole (696-62-8) → bis(4-methoxyphenyl)sulfide (3393-77-9)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium tert-butylate; bis[2-(diphenylphosphino)phenyl] ether; In toluene; at 100 ℃; for 2h;

DOI:10.1016/S0040-4020(01)00157-0

Reference yield: 99.0%

para-iodoanisole (696-62-8) → bis(4-methoxyphenyl)sulfide (3393-77-9)

Guidance literature:

With potassium carbonate; thiourea; In ethanol; for 0.75h; Reflux;

DOI:10.1002/aoc.5260

Reference yield: 98.0%

1-bromo-4-methoxy-benzene (104-92-7) + 4-Methoxybenzenethiol (696-63-9) → bis(4-methoxyphenyl)sulfide (3393-77-9)

Guidance literature:

With (R)-1-[(S_P)-2-(dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; palladium diacetate; sodium t-butanolate; In 1,2-dimethoxyethane; at 110 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jo802594d

upstream raw materials:

4-Methoxybenzenethiol

para-iodoanisole

4,4'-dimethoxyphenyl disulfide

methoxybenzene

Downstream raw materials:

bis(4-methoxyphenyl) sulfoxide

bis(p-anisyl)sulfone

4,4'-Dimethoxybiphenyl

phenylsulfonyl fluoride

Refernces

• 1、 Chen, Hui,Liu, Wanlu,Laemont, Andreas,Krishnaraj, Chidharth,Feng, Xiao,Rohman, Fadli,Meledina, Maria,Zhang, Qiqi,Van Deun, Rik,Leus, Karen,Van Der Voort, Pascal. "A Visible-Light-Harvesting Covalent Organic Framework Bearing Single Nickel Sites as a Highly Efficient Sulfur–Carbon Cross-Coupling Dual Catalyst". supporting information. p. 10820 - 10827. Retrieved 2021/04/09.
• 2、 Morandi, Bill,Rivero-Crespo, Miguel A.,Toupalas, Georgios. "Preparation of Recyclable and Versatile Porous Poly(aryl thioether)s by Reversible Pd-Catalyzed C–S/C–S Metathesis". supporting information. p. 21331 - 21339. Retrieved 2021/12/17.