(R)-1-indanyl butyrate

Base Information

• Chemical Name: (R)-1-indanyl butyrate
• CAS No.: 158529-97-6
• Molecular Formula: C₁₃H₁₆O₂
• Molecular Weight: 204.269
• Mol file: 158529-97-6.mol

Synonyms:(R)-1-indanyl butyrate

Chemical Property of (R)-1-indanyl butyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-indanyl butyrate

There total 14 articles about (R)-1-indanyl butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

isopropyl butyrate (638-11-9) + 1-Indanol (6351-10-6) → (R)-indan-1-ol (697-64-3) + (S)-indanol (25501-32-0) + inden-1-one (83-33-0) + (R)-1-indanyl butyrate (158529-97-6)

Guidance literature:

With [(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one; In toluene; at 70 ℃; for 40h; under 142.511 Torr;

DOI:10.1016/j.tetasy.2005.02.028

Reference yield: 24.0%

1-Indanol (6351-10-6) + <1,1'-Binaphthalene>-2,2'-diol dibutanoate (100465-50-7) → (S)-indanol (25501-32-0) + (S)-[1,1']-binaphthalenyl-2,2'-diol (18531-99-2) + (R)-1-indanyl butyrate (158529-97-6) + (R)-1,1'-bi-2-naphthyl-2,2'-dibutyrate

Guidance literature:

porcine pancreatic lipase; In diethyl ether; benzene; Product distribution; Heating; bovine albumin (fraction V), triple enantioselective transacylation catalyzed by various enzymes;

DOI:10.1016/S0040-4039(00)61726-4

Reference yield: 23.0%

1-Indanol (6351-10-6) + <1,1'-Binaphthalene>-2,2'-diol dibutanoate (100465-50-7) → (S)-[1,1']-binaphthalenyl-2,2'-diol (18531-99-2) + (R)-1-indanyl butyrate (158529-97-6)

Guidance literature:

porcine pancreatic lipase; In diethyl ether; benzene; Heating; bovine albumin (fraction V);

DOI:10.1016/S0040-4039(00)61726-4

upstream raw materials:

1-Indanol

<1,1'-Binaphthalene>-2,2'-diol dibutanoate

<1,1'-Binaphthalene>-2,2'-diol butanoate

vinyl n-butyrate

Downstream raw materials:

(R)-indan-1-ol

Refernces

• 1、 Lin, Gialih,Liu, Shih-Huang,Chen, Show-Jane,Wu, Fang-Chen,Sun, Hwey-Lin. ""Triple enantioselection" by an enzyme-catalyzed transacylation reaction". . p. 6057 - 6058. Retrieved 1993.
• 2、 Lin, Gialih,Lin, Wen-Yuan,Shieh, Chuen-Tzwu. "The enhancement of enantioselectivities for lipase-catalyzed reactions by using carbamates". . p. 8881 - 8884. Retrieved 2007/10/03.