C₄₀H₄₂O₈

Base Information

• Chemical Name: C₄₀H₄₂O₈
• CAS No.: 1610701-21-7
• Molecular Formula: C₄₀H₄₂O₈
• Molecular Weight: 650.769
• Mol file: 1610701-21-7.mol

Synonyms:C₄₀H₄₂O₈

Chemical Property of C₄₀H₄₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₄₂O₈

There total 3 articles about C₄₀H₄₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-diiodo-3,3',5,5'-tetramethylbiphenyl (1140509-33-6) + diethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzene-dicarboxylate (1309982-02-2) → C40H42O8 (1610701-21-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride; In 1,2-dimethoxyethane; for 72h; Inert atmosphere; Reflux;

DOI:10.1021/ja5023283

Reference yield:

3,3',5,5'-tetramethylbenzidine (54827-17-7) → C40H42O8 (1610701-21-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium nitrite; hydrogenchloride / water / 0.75 h / 0 °C

1.2: 4 h / 20 °C / Cooling with ice

2.1: cesium fluoride; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane / 72 h / Schlenk technique; Inert atmosphere; Reflux

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride; sodium nitrite; In 1,2-dimethoxyethane; water;

Reference yield:

5-aminoisophthalic acid (99-31-0) → C40H42O8 (1610701-21-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: thionyl chloride / 5 h / Reflux

2.1: sodium nitrite; hydrogenchloride / water / 0.75 h / 0 °C

2.2: 4 h / 20 °C / Cooling with ice

3.1: palladium diacetate; potassium acetate / N,N-dimethyl-formamide / 24 h / 90 °C

4.1: cesium fluoride; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane / 72 h / Schlenk technique; Inert atmosphere; Reflux

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; thionyl chloride; potassium acetate; palladium diacetate; cesium fluoride; sodium nitrite; In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;

upstream raw materials:

4,4'-diiodo-3,3',5,5'-tetramethylbiphenyl

diethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzene-dicarboxylate

5-aminoisophthalic acid

3,3',5,5'-tetramethylbenzidine

Downstream raw materials:

2′,3″,5″,6′-tetramethyl-[1,1′:4′,1″:4″,1?-quaterphenyl]3,3?,5,5?-tetracarboxylic acid

Refernces

• 1、 -. "Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks". Page/Page column 35. . Retrieved 2016/01/20.
• 2、 Liu, Tian-Fu,Zou, Lanfang,Feng, Dawei,Chen, Ying-Pin,Fordham, Stephen,Wang, Xuan,Liu, Yangyang,Zhou, Hong-Cai. "Stepwise synthesis of robust metal-organic frameworks via postsynthetic metathesis and oxidation of metal nodes in a single-crystal to single-crystal transformation". supporting information. p. 7813 - 7816. Retrieved 2014/06/23.