O-Mesitylenesulfonylhydroxylamine

Base Information

• Chemical Name: O-Mesitylenesulfonylhydroxylamine
• CAS No.: 36016-40-7
• Molecular Formula: C9H13NO3S
• Molecular Weight: 215.273
• Hs Code.: 2922199090
• Mol file: 36016-40-7.mol

Synonyms:Hydroxylamine,O-(mesitylsulfonyl)- (6CI);Hydroxylamine, O-[(2,4,6-trimethylphenyl)sulfonyl]-(9CI);2-[(Aminooxy)sulfonyl]-1,3,5-trimethylbenzene;O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine;

Chemical Property of O-Mesitylenesulfonylhydroxylamine

Chemical Property:

• Vapor Pressure: 1.75E-06mmHg at 25°C
• Melting Point: 93-94 °C
• Refractive Index: 1.556
• Boiling Point: 350.587 °C at 760 mmHg
• PKA: -4.59±0.70(Predicted)
• Flash Point: 165.83 °C
• PSA: 77.77000
• Density: 1.24 g/cm³
• LogP: 2.97190
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly)

Purity/Quality:

99.0% ^*data from raw suppliers

o-Mesitylenesulfonylhydroxylamine(containamin.of10%H2O) 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O-Mesitylenesulfonylhydroxylamine

There total 17 articles about O-Mesitylenesulfonylhydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(tert-butoxycarbonyl)-O-(mesitylsulfonyl)hydroxylamine (36016-39-4) → mesitylenesulfonylhydroxylamine (36016-40-7)

Guidance literature:

With trifluoroacetic acid; at 0 ℃; for 1.5h;

Reference yield: 93.0%

ethyl O-(2-mesitylenesulfonyl)acetohydroxamate (38202-27-6) → mesitylenesulfonylhydroxylamine (36016-40-7)

Guidance literature:

With perchloric acid; In 1,4-dioxane; water; at 0 ℃; for 0.116667h;

DOI:10.1021/ja8026168

Reference yield: 84.0%

2-mesitylenesulphonyl chloride (773-64-8) → mesitylenesulfonylhydroxylamine (36016-40-7)

Guidance literature:

2-mesitylenesulphonyl chloride; With triethylamine; at 20 ℃;

With perchloric acid; Neat (no solvent);

upstream raw materials:

O-(2,4,6-trimethylphenylsulfonyl)-N,N-bis(trimethylsilyl)hydroxylamine

ethyl O-(2-mesitylenesulfonyl)acetohydroxamate

2-mesitylenesulphonyl chloride

N-(tert-butoxycarbonyl)-O-(mesitylsulfonyl)hydroxylamine

Downstream raw materials:

3-amino-2-formylamino-thiazolium; 2,4,6-trimethyl-benzenesulfonate

3-amino-2-methyl-benzothiazolium; 2,4,6-trimethyl-benzenesulfonate

2-acetylamino-3-amino-benzothiazolium; 2,4,6-trimethyl-benzenesulfonate

3-amino-2-benzoylamino-thiazolium; 2,4,6-trimethyl-benzenesulfonate

Refernces

• 1、 Kumar, Arun Babu,Manetsch, Roman. "Ammonia-free synthesis of 3-trifluoromethyl-3-phenyldiaziridine". . p. 626 - 631. Retrieved 2018.
• 2、 -. "SUBSTITUTED 1,5-NAPHTHYRIDINES OR QUINOLINES AS ALK5 INHIBITORS". . . Retrieved 2021/05/29.
• 3、 -. "N-(4-FLUOROPHENYL)-5-PHENYL-[1,2,4] TRIAZOLO [1,5-A] PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND THEIR SYNTHESIS THEREOF". . . Retrieved 2021/08/20.