trans-3-phenyloxiranecarboxylic acid potassium salt

Base Information

• Chemical Name: trans-3-phenyloxiranecarboxylic acid potassium salt
• CAS No.: 100750-44-5
• Molecular Formula: C₉H₇O₃*K
• Molecular Weight: 202.251
• Mol file: 100750-44-5.mol

Synonyms:trans-3-phenyloxiranecarboxylic acid potassium salt

Chemical Property of trans-3-phenyloxiranecarboxylic acid potassium salt

Chemical Property:

Purity/Quality:

POTASSIUM-3-PHENYLOXIRANE-2-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-3-phenyloxiranecarboxylic acid potassium salt

There total 7 articles about trans-3-phenyloxiranecarboxylic acid potassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(E)-3-phenylacrylic acid (140-10-3) → trans-3-phenyloxiranecarboxylic acid potassium salt (100750-44-5)

Guidance literature:

With Oxone; disodium ethylenediaminetetraacetic acid; sodium hydrogencarbonate; In acetone; at 24 - 27 ℃; for 2h; pH = 7.4;

DOI:10.1021/jo00360a059

Reference yield: 82.0%

ethyl cis-3-phenylglycidate (121-39-1,2272-49-3,2272-55-1,54276-44-7,56791-22-1,126060-73-9,130321-77-6,130321-78-7,130605-53-7) → potassium cis-3-phenyloxiranecarboxylate (19190-78-4,54265-94-0,54323-79-4,100750-44-5,133534-44-8,137472-83-4,137566-93-9)

Guidance literature:

With potassium hydroxide; In ethanol;

DOI:10.1002/hlca.200390160

Reference yield:

2,3-epoxy-3-phenylpropanoic acid (5694-02-0) → trans-3-phenyloxiranecarboxylic acid potassium salt (100750-44-5)

Guidance literature:

With potassium hydroxide; In ethanol; Cooling with ice;

DOI:10.1021/acscatal.9b01557

upstream raw materials:

ethyl cis-3-phenylglycidate

ethyl 3-phenylglycidate

(E)-3-phenylacrylic acid

benzaldehyde

Downstream raw materials:

(RS,SR) 2-hydroxy-3-(2-ethoxyphenoxy)-3-benzenepropanoic acid

(RS,RS) 2-hydroxy-3-(2-ethoxyphenoxy)-3-benzenepropanoic acid

(RS,SR) 2-hydroxy-3-phenoxy-3-benzenepropanoic acid

(RS,RS) 2-hydroxy-3-phenoxy-3-benzenepropanoic acid

Refernces

• 1、 Shee, Prakash K.,Ratnayake, Nishanka Dilini,Walter, Tyler,Goethe, Olivia,Onyeozili, Edith Ndubuaku,Walker, Kevin D.. "Exploring the scope of an α/β-aminomutase for the amination of cinnamate epoxides to arylserines and arylisoserines". . p. 7418 - 7430. Retrieved 2019/08/20.
• 2、 Khanjin, Nikolai A.,Hesse, Manfred. "Synthesis of the spermidine alkaloids (-)-(2R,3R)- and (-)-(2R,3S)-3-hydroxycelacinnine: Macrocyclization with oxirane-ring opening and inversion via cyclic sulfamidates". . p. 2028 - 2057. Retrieved 2007/10/03.