4-ACETYLAMINO-2,6-ANHYDRO-3,4-DIDEOXY-D-GLYCERO-D-GALACTONON-2-ENONIC ACID

Base Information

• Chemical Name: 4-ACETYLAMINO-2,6-ANHYDRO-3,4-DIDEOXY-D-GLYCERO-D-GALACTONON-2-ENONIC ACID
• CAS No.: 263155-11-9
• Molecular Formula: C₁₁H₁₇NO₈
• Molecular Weight: 291.258
• Mol file: 263155-11-9.mol

Synonyms:4-Acetylamino-Kdn2en, iso-Neu4Ac2en;4-Acetamido-3-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid;

Chemical Property of 4-ACETYLAMINO-2,6-ANHYDRO-3,4-DIDEOXY-D-GLYCERO-D-GALACTONON-2-ENONIC ACID

Chemical Property:

• Appearance/Colour: White solid
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 189-191°C
• Refractive Index: 1.613
• Boiling Point: 773.428 °C at 760 mmHg
• PKA: 3.89±0.70(Predicted)
• Flash Point: 421.554 °C
• PSA: 156.55000
• Density: 1.588 g/cm³
• LogP: -2.67570

Purity/Quality:

99% ^*data from raw suppliers

4-Acetamido-2,6-anhydro-3,4-dideoxy-D-glycero-D-galactonon-2-enonic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A potential inhibitor of virus sialidase.

Technology Process of 4-ACETYLAMINO-2,6-ANHYDRO-3,4-DIDEOXY-D-GLYCERO-D-GALACTONON-2-ENONIC ACID

There total 2 articles about 4-ACETYLAMINO-2,6-ANHYDRO-3,4-DIDEOXY-D-GLYCERO-D-GALACTONON-2-ENONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 5,7,8,9-tetra-O-acetyl-4-acetylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-galacto-non-2-enonate (173467-18-0) → 4-acetylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-galacto-non-2-enonic acid (263155-11-9)

Guidance literature:

With barium dihydroxide; In water; at 20 ℃; for 5h;

DOI:10.1016/S0008-6215(99)00236-0

Reference yield: 75.0%

methyl 5,7,8,9-tetra-O-acetyl-4-acetylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-talo-non-2-enonate (173467-19-1) → 4-acetylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-talo-non-2-enonic acid (263155-11-9)

Guidance literature:

With barium dihydroxide; In water; at 20 ℃; for 5h;

DOI:10.1016/S0008-6215(99)00236-0

upstream raw materials:

methyl 5,7,8,9-tetra-O-acetyl-4-acetylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-talo-non-2-enonate

methyl 5,7,8,9-tetra-O-acetyl-4-acetylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-galacto-non-2-enonate

Refernces