2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE

Base Information

• Chemical Name: 2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE
• CAS No.: 4515-24-6
• Molecular Formula: C14H22N2O8
• Molecular Weight: 346.337
• Hs Code.: 2938909090
• Mol file: 4515-24-6.mol

Synonyms:Glucopyranosylamine,2-acetamido-2-deoxy-, 3,4,6-triacetate (7CI);Glucopyranosylamine,2-acetamido-2-deoxy-, 3,4,6-triacetate, b-D- (8CI);

Chemical Property of 2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 203-205°C
• Refractive Index: 1.505
• Boiling Point: 514.456 °C at 760 mmHg
• Flash Point: 264.934 °C
• PSA: 143.25000
• Density: 1.293 g/cm³
• LogP: -0.30760
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform, Methanol

Purity/Quality:

99% ^*data from raw suppliers

2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE

There total 1 articles about 2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosylamine (4515-24-6) + 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl azide (6205-69-2)

Guidance literature:

Reference yield: 96.0%

2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosylamine (4515-24-6) + benzyl hydrogen (S)-2-(tert-butyldimethylsilyloxy)succinate (309730-43-6) → (S)-2-(tert-Butyl-dimethyl-silanyloxy)-N-((2R,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-2-yl)-succinamic acid benzyl ester (309730-45-8)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

Reference yield: 93.0%

2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosylamine (4515-24-6) + Noc-Asp(OH)-OtBu (116864-67-6) → (S)-N-((2R,3R,4R,5S,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-2-yl)-2-[(E)-3-(4-nitro-phenyl)-allyloxycarbonylamino]-succinamic acid tert-butyl ester (116864-79-0)

Guidance literature:

With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In dichloromethane; at 20 ℃; for 24h;

Downstream raw materials:

Z-Asnβ-(Ac3GlcNAc)α-OBu^t

2-acetamido-3,4,6-tri-O-acetyl-1-N-[1-benzyl-N-(benzyloxy)carbonyl-L-aspart-4-oyl]-2-deoxy-β-D-glucopyranosylamine

2-acetamido-3,4,6-tri-O-acetyl-1-N-<1-benzyl N-(tert-butyloxycarbonyl)-L-4-aspart-4-oyl>-2-deoxy-D-glucopyranosylamine

Z-Asnα-(Ac3GlcNAc)β-OBu^t

Refernces