1H-INDOL-3-YLBORONIC ACID

Base Information

• Chemical Name: 1H-INDOL-3-YLBORONIC ACID
• CAS No.: 741253-05-4
• Molecular Formula: C8H8 B N O2
• Molecular Weight: 160.968
• Hs Code.: 2933998090
• Mol file: 741253-05-4.mol

Synonyms:Boronicacid, 1H-indol-3-yl- (9CI); 1H-Indol-3-ylboronic acid; Indol-3-ylboronic acid

Chemical Property of 1H-INDOL-3-YLBORONIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 433.229°C at 760 mmHg
• PKA: 9.20±0.30(Predicted)
• Flash Point: 215.81°C
• PSA: 56.25000
• Density: 1.331g/cm³
• LogP: -0.15230
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

1H-Indol-3-ylboronic acid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-INDOL-3-YLBORONIC ACID

There total 1 articles about 1H-INDOL-3-YLBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C8H6BBr2N + potassium hydroxide → (1H-indol-3-yl)boronic acid (741253-05-4)

Guidance literature:

With air; In water; 1,2-dichloro-ethane; at 10 - 60 ℃; pH=12 - 13;

Reference yield: 99.0%

1-benzyl-1H-pyrrole-2,5-dione (1631-26-1) + (1H-indol-3-yl)boronic acid (741253-05-4) → 1-benzyl-3-(1H-indole-3-yl)pyrrolidine-2,5-dione (408521-57-3)

Guidance literature:

With RhOH(cod)2; triethylamine; In 1,4-dioxane; water; at 20 ℃;

DOI:10.1016/j.bmcl.2008.10.025

Reference yield: 88.7%

(1H-indol-3-yl)boronic acid (741253-05-4) + C15H14BrN3O2Se → 7-(3,4-dimethoxy-5-(methylselanyl)phenyl)-2-(1H-indol-3-yl)-pyrazolo[1,5-a]pyrimidine

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In water; N,N-dimethyl-formamide; at 95 ℃; for 12h;

DOI:10.1021/acs.jmedchem.0c01837

Downstream raw materials:

1-benzyl-3-(1H-indole-3-yl)pyrrolidine-2,5-dione

C₂₀H₁₄N₄

2,3-bis(1H-indol-3-yl)-N-benzylmaleimide

methyl 1-benzyl-9H-carbazole-3-carboxylate

Refernces