FMOC-LYS(BOC)(ISOPROPYL)-OH

Base Information

• Chemical Name: FMOC-LYS(BOC)(ISOPROPYL)-OH
• CAS No.: 201003-48-7
• Molecular Formula: C₂₉H₃₈N₂O₆
• Molecular Weight: 510.631
• Mol file: 201003-48-7.mol

Synonyms:Fmoc-Lys(Boc)(isopropyl)-OH; N-(9-Fluorenylmethyloxycarbonyl)-N'-tert-butoxycarbonyl-N'-isopropyl-L-lysine

Chemical Property of FMOC-LYS(BOC)(ISOPROPYL)-OH

Chemical Property:

• Boiling Point: 677.1±55.0 °C(Predicted)
• PKA: 3.88±0.21(Predicted)
• PSA: 105.17000
• Density: 1.172±0.06 g/cm3(Predicted)
• LogP: 6.18500
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

Fmoc-l-lys(boc,ipr)-oh ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of FMOC-LYS(BOC)(ISOPROPYL)-OH

There total 3 articles about FMOC-LYS(BOC)(ISOPROPYL)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H30N2O4 (871811-39-1) + di-tert-butyl dicarbonate (24424-99-5) → Fmoc-L-Lys(iPr,Boc)-OH (201003-48-7)

Guidance literature:

With sodium carbonate; In tert-butyl alcohol; at 20 ℃;

Reference yield:

Fmoc-Lys(tert-butoxycarbonyl) (71989-26-9) → Fmoc-L-Lys(iPr,Boc)-OH (201003-48-7)

Guidance literature:

Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 20 °C

2: trifluoroacetic acid / methanol / 2 h / 20 °C

3: sodium carbonate / tert-butyl alcohol / 20 °C

With sodium carbonate; trifluoroacetic acid; In methanol; dichloromethane; tert-butyl alcohol;

Reference yield:

Fmoc-Lys-OH (105047-45-8) → Fmoc-L-Lys(iPr,Boc)-OH (201003-48-7)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / methanol / 2 h / 20 °C

2: sodium carbonate / tert-butyl alcohol / 20 °C

With sodium carbonate; trifluoroacetic acid; In methanol; tert-butyl alcohol;

upstream raw materials:

Fmoc-Lys(tert-butoxycarbonyl)

C₂₄H₃₀N₂O₄

di-tert-butyl dicarbonate

Fmoc-Lys-OH

Refernces