Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

Base Information Edit

Chemical Name:Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate
CAS No.:89151-44-0
Molecular Formula:C12H23NO3
Molecular Weight:229.32
Hs Code.:2933399090
European Community (EC) Number:692-472-5
DSSTox Substance ID:DTXSID30357554
Nikkaji Number:J1.098.029A
Wikidata:Q72449564
Mol file:89151-44-0.mol

Synonyms:89151-44-0;N-Boc-4-piperidineethanol;Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate;1-Boc-4-(2-hydroxyethyl)piperidine;MFCD03427086;N-TERT-BUTOXYCARBONYL-4-PIPERIDINEETHANOL;1-(tert-Butoxycarbonyl)-4-(2-hydroxyethyl)piperidine;1-PIPERIDINECARBOXYLIC ACID, 4-(2-HYDROXYETHYL)-, 1,1-DIMETHYLETHYL ESTER;N-(tert-Butoxycarbonyl)-4-piperidineethanol;4-(2-HYDROXYETHYL)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Boc-4-(2-hydroxy-ethyl)-piperidine;N-Boc-4-piperidine ethanol;N-Boc-4-piperidine-ethanol;SCHEMBL310405;DTXSID30357554;N-Boc-4-piperidineethanol, 97%;YBNJZIDYXCGAPX-UHFFFAOYSA-N;CS-M1539;N-BOC-2-(piperidin-4-yl)ethanol;STR09751;N-Boc-4-(2-hydroxyethyl)piperidine;4-(2-Hydroxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester;BBL101228;STL555024;AKOS005258053;N-Boc-4-(2-hydroxy-ethyl)-piperidine;PB33688;2-(N-BOC-PIPERIDIN-4-YL)ETHANOL;AC-29348;SY002535;TS-00599;1-t-butoxycarbonyl-4-hydroxyethylpiperidine;1-(tert-butoxycarbonyl)piperidin -4-ethanol;1-(tert-Butoxycarbonyl)piperidine-4-ethanol;1-t-Butyloxycarbonyl-4-hydroxyethylpiperidine;AM20120285;FT-0650495;2-(n-tert-butoxycarbonyl-4-piperidyl)ethanol;2-(1-tert-butoxycarbonylpiperidin-4-yl)ethanol;2-(N-tert-butyloxycarbonyl-4-piperidyl)ethanol;EN300-154218;N-tert-butoxycarbonyl-2-(4-piperidinyl)ethanol;1-t-butoxycarbonyl-4-(2-hydroxyethyl) piperidine;1-t-Butyloxycarbonyl-4-(2-hydroxyethyl)piperidine;2-(1-(tert-butoxycarbonyl)-4-piperidyl)-ethanol;2-[1-(tert-Butoxycarbonyl)piperidin-4-yl]ethanol;A843074;t-butyl 4-(2-hydroxyethyl)piperidin-1-carboxylate;1-tert-butoxycarbonyl-4-(2-hydroxyethyl)piperidine;4-(2-hydroxyeth-1-yl)-1-t-butoxycarbonylpiperidine;4-(2-hydroxyethyl)-1-(t-butoxycarbonyl)-piperidine;4-(2-hydroxyethyl)-1-tert-butoxycarbonylpiperidine;J-524597;t-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate;tert-Butyl 4-(hydroxyethyl)piperidine-1-carboxylate;1-(t-butyloxycarbonyl)-4-(2-hydroxyethyl)piperidine;tert-butyl 4-(2 hydroxyethyl)piperidine-1-carboxylate;tert-butyl 4-(2hydroxyethyl)piperidine-1-carboxylate;tert-butyl-4-(2-hydroxyethyl)piperidine-1-carboxylate;1-(tert-Butoxycarbonyl)-4-(2-hydroxyethyl)-piperidine;4-(2-hydroxy-1-ethyl)-1-tert-butoxycarbonyl-piperidine;4-(2-Hydroxyeth-1-yl)-1-tert-butoxycarbonylpiperidine;tert-butyl 4-(2-hydroxyethyl)-piperidine-1-carboxylate;1,1-dimethylethyl 4-(2-hydroxyethyl)-1-piperidine-carboxylate;1,1-dimethylethyl 4-(2-hydroxyethyl)-1-piperidinecarboxylate;t-butyl 4-(2-hydroxyethyl)tetrahydropyridine-1(2H)-carboxylate;4-(2-hydroxy-ethyl)piperidine-1-carboxylic acid tert-butyl ester;4-(2-hydroxyethyl)-piperidine-1-carboxylic acid tert-butyl ester;t-butyl 4-(2-hydroxyethyl)tetrahydro-pyridine-1(2H)-carboxylate;1-Piperidinecarboxylicacid, 4-(2-hydroxyethyl)-, 1,1-dimethylethyl ester;tert-butyl 2-hydroxy-3-(4-piperidyl)propanoate;N-BOC-4-PIPERIDINEETHANOL

Suppliers and Price of Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-BOC-4-piperidine-β-ethanol
10 g
$ 200.00

SynQuest Laboratories
4-(2-Hydroxyethyl)piperidine, N-Boc protected
100 g
$ 440.00

SynQuest Laboratories
4-(2-Hydroxyethyl)piperidine, N-Boc protected
25 g
$ 136.00

SynQuest Laboratories
4-(2-Hydroxyethyl)piperidine, N-Boc protected
5 g
$ 48.00

SynChem
N-tert-Butoxycarbonyl-4-piperidineethanol 95+%
5 g
$ 90.00

SynChem
N-tert-Butoxycarbonyl-4-piperidineethanol 95+%
1 g
$ 25.00

SynChem
N-tert-Butoxycarbonyl-4-piperidineethanol 95+%
10 g
$ 165.00

Sigma-Aldrich
N-Boc-4-piperidineethanol 97%
5g
$ 126.00

Sigma-Aldrich
N-Boc-4-piperidineethanol 97%
1g
$ 41.30

Oakwood
N-Boc-4-Piperidineethanol 97%
1g
$ 15.00

Total 123 raw suppliers

Chemical Property of Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:n20/D 1.4730(lit.)
Boiling Point:324.066 °C at 760 mmHg
PKA:15.10±0.10(Predicted)
Flash Point:149.79 °C
PSA：49.77000
Density:1.043 g/cm³
LogP:1.95380
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:229.16779360
Heavy Atom Count:16
Complexity:227

Purity/Quality:

99.0% ^*data from raw suppliers

N-BOC-4-piperidine-β-ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)CCO
Uses N-BOC-4-piperidine-β-ethanol is used to prepare anilinoquinazoline VEGF receptor tyrosine kinase inhibitors with antitumor activities. It is also used to synthesize 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists with antiviral activities.

Technology Process of Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

There total 26 articles about Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%