Technology Process of (4Z,7Z)-12-(2,3,4,5-Tetramethoxy-6-methyl-phenyl)-dodeca-4,7-dien-1-ol
There total 11 articles about (4Z,7Z)-12-(2,3,4,5-Tetramethoxy-6-methyl-phenyl)-dodeca-4,7-dien-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
quinoline; hydrogen;
Lindlar's catalyst;
In
ethyl acetate;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) ethyl magnesium bromide, 2.) copper(I) bromide / 1.) THF, 2.) 50 deg C, 2 h
2: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
3: 72 percent / hydrogen, quinoline / Lindlar catalyst / ethyl acetate / Ambient temperature
With
quinoline; ethylmagnesium bromide; hydrogen; toluene-4-sulfonic acid; copper(I) bromide;
Lindlar's catalyst;
In
methanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 9 steps
1: triethylamine / CH2Cl2 / 1 h / -5 °C
2: sodium iodide / acetone / 2 h / 50 °C
3: 1.) sodium amide / 1.) Et2O, liquid ammonia, -50 deg C - -40 deg C, 60 min, 2.) -50 deg C - -40 deg C, 100 min
4: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
5: triethylamine / CH2Cl2 / 1 h / -5 °C
6: sodium iodide / acetone / 2 h / 50 °C
7: 1.) ethyl magnesium bromide, 2.) copper(I) bromide / 1.) THF, 2.) 50 deg C, 2 h
8: toluene-p-sulphonic acid / methanol / 0.5 h / 70 °C
9: 72 percent / hydrogen, quinoline / Lindlar catalyst / ethyl acetate / Ambient temperature
With
quinoline; ethylmagnesium bromide; hydrogen; toluene-4-sulfonic acid; sodium amide; triethylamine; sodium iodide; copper(I) bromide;
Lindlar's catalyst;
In
methanol; dichloromethane; ethyl acetate; acetone;