6-Methyl-3-pyridineethanol

Base Information

• Chemical Name: 6-Methyl-3-pyridineethanol
• CAS No.: 100189-17-1
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Hs Code.: 2933399090
• Mol file: 100189-17-1.mol

Synonyms:2-(6-methylpyridin-3-yl)ethanol;

Chemical Property of 6-Methyl-3-pyridineethanol

Chemical Property:

• Vapor Pressure: 0.014mmHg at 25°C
• Melting Point: 38 °C
• Refractive Index: 1.535
• Boiling Point: 246.739 °C at 760 mmHg
• PKA: 14.61±0.10(Predicted)
• Flash Point: 103.025 °C
• PSA: 33.12000
• Density: 1.061 g/cm³
• LogP: 0.92480
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

6-Methyl-3-pyridineethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6-Methyl-3-pyridineethanol is a reactant used in organic synthesis.

Technology Process of 6-Methyl-3-pyridineethanol

There total 6 articles about 6-Methyl-3-pyridineethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(6-methylpyridin-3-yl)acetic acid (19733-96-1) → 2-(6-methylpyridin-3-yl) ethan-1-ol (100189-17-1)

Guidance literature:

With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

Reference yield:

2-methyl-5-vinylpyridine (140-76-1,25038-86-2) → 2-(6-methylpyridin-3-yl) ethan-1-ol (100189-17-1)

Guidance literature:

2-methyl-5-vinylpyridine; With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 0 ℃; Reflux; Inert atmosphere;

With dihydrogen peroxide; In tetrahydrofuran; water; for 1h; Inert atmosphere;

DOI:10.1021/ol2008268

Reference yield:

1-(6-methyl-pyridin-3-yl)-ethanone (36357-38-7) → 2-(6-methylpyridin-3-yl) ethan-1-ol (100189-17-1)

Guidance literature:

With bromine; Behandeln des Reaktionsprodukts mit Kaliumacetat in Aethanol und nachfolgend Reduktion;

DOI:10.1021/ja01878a518

upstream raw materials:

1-(6-methyl-pyridin-3-yl)-ethanone

2-methyl-5-vinylpyridine

5-bromo-2-methylpyridine

2-(6-methylpyridin-3-yl)acetic acid

Downstream raw materials:

5-(2-bromoethyl)-2-methylpyridine

dimebon

Refernces

• 1、 Schmelkes,Joiner. "-". . p. 2562. Retrieved 1939.
• 2、 -. "Tetraaza-cyclopenta[a]indenyl derivatives". . . Retrieved 2015/01/18.