5-HYDRAZINOCARBONYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID PHENYLAMIDE

Base Information

• Chemical Name: 5-HYDRAZINOCARBONYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID PHENYLAMIDE
• CAS No.: 89562-40-3
• Molecular Formula: C14H32N2
• Molecular Weight: 245.24
• Mol file: 89562-40-3.mol

Synonyms:1H-Imidazole-4-carboxylicacid, 5-[(phenylamino)carbonyl]-, hydrazide (9CI);

Chemical Property of 5-HYDRAZINOCARBONYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID PHENYLAMIDE

Chemical Property:

• Refractive Index: 1.716
• PSA: 112.90000
• Density: 1.465g/cm³
• LogP: 1.42970

Purity/Quality:

98%min ^*data from raw suppliers

5-Hydrazinocarbonyl-3H-imidazole-4-carboxylic acid phenylamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-HYDRAZINOCARBONYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID PHENYLAMIDE

There total 3 articles about 5-HYDRAZINOCARBONYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID PHENYLAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5,10-dioxo-N1,N6-diphenyl-5,10-dihydrodiimidazo[1,5-a:1',5'-d]pyrazine-1,6-dicarboxamide (89562-34-5) → 5-Hydrazinocarbonyl-1H-imidazole-4-carboxylic acid phenylamide (89562-40-3)

Guidance literature:

With hydrazine hydrate; In N,N-dimethyl-formamide; for 1h; Ambient temperature;

DOI:10.1007/BF00758293

Reference yield:

4H,9H-diimidazo<1,5-a; 1',5'-d>pyrazine-5,10-dione-1,6-dicarboxylic dichloride (59157-06-1) → 5-Hydrazinocarbonyl-1H-imidazole-4-carboxylic acid phenylamide (89562-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / Et₃N / CHCl₃ / 1 h / Ambient temperature

2: 80 percent / hydrazine hydrate / dimethylformamide / 1 h / Ambient temperature

With hydrazine hydrate; triethylamine; In chloroform; N,N-dimethyl-formamide;

DOI:10.1007/BF00758293

Reference yield:

aniline (62-53-3) → 5-Hydrazinocarbonyl-1H-imidazole-4-carboxylic acid phenylamide (89562-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / Et₃N / CHCl₃ / 1 h / Ambient temperature

2: 80 percent / hydrazine hydrate / dimethylformamide / 1 h / Ambient temperature

With hydrazine hydrate; triethylamine; In chloroform; N,N-dimethyl-formamide;

DOI:10.1007/BF00758293

upstream raw materials:

5,10-dioxo-N¹,N⁶-diphenyl-5,10-dihydrodiimidazo[1,5-a:1',5'-d]pyrazine-1,6-dicarboxamide

4H,9H-diimidazo<1,5-a; 1',5'-d>pyrazine-5,10-dione-1,6-dicarboxylic dichloride

aniline

Downstream raw materials:

5-[1-(5-Nitro-furan-2-yl)-meth-(E)-ylidene-hydrazinocarbonyl]-1H-imidazole-4-carboxylic acid phenylamide

Refernces