Technology Process of Lensiprazine
There total 7 articles about Lensiprazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: H2 / Pd/C / ethanol; ethyl acetate / 24 h
2: chlorobenzene / 69 h / Heating
3: KI; DIPEA / acetonitrile / 18 h / Heating
With
hydrogen; N-ethyl-N,N-diisopropylamine; potassium iodide;
palladium on activated charcoal;
In
ethanol; ethyl acetate; chlorobenzene; acetonitrile;
DOI:10.1021/jm050148z
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 79 percent / Ph3P; DIAD / tetrahydrofuran / 96 h / 20 °C
2: H2 / Pd/C / ethanol; ethyl acetate / 24 h
3: chlorobenzene / 69 h / Heating
4: KI; DIPEA / acetonitrile / 18 h / Heating
With
di-isopropyl azodicarboxylate; hydrogen; N-ethyl-N,N-diisopropylamine; triphenylphosphine; potassium iodide;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; ethyl acetate; chlorobenzene; acetonitrile;
1: Mitsunobu reaction;
DOI:10.1021/jm050148z
