phthalic acid mono-(4-methoxy-benzyl ester)

Base Information

• Chemical Name: phthalic acid mono-(4-methoxy-benzyl ester)
• CAS No.: 33533-58-3
• Molecular Formula: C₁₆H₁₄O₅
• Molecular Weight: 286.284
• Mol file: 33533-58-3.mol

Synonyms:phthalic acid mono-(4-methoxy-benzyl ester)

Chemical Property of phthalic acid mono-(4-methoxy-benzyl ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phthalic acid mono-(4-methoxy-benzyl ester)

There total 3 articles about phthalic acid mono-(4-methoxy-benzyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

phthalic acid 1-(4-methoxy-benzyl) ester 2-(1,2,3,4-tetrahydro-naphthalen-1-yl) ester (243128-08-7) → phthalic acid mono-(4-methoxy-benzyl ester) (33533-58-3)

Guidance literature:

With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(99)01040-0

Reference yield:

phthalic anhydride (85-44-9) + 4-Methoxybenzyl alcohol (105-13-5) → phthalic acid mono-(4-methoxy-benzyl ester) (33533-58-3)

Guidance literature:

With pyridine;

Reference yield:

→ phthalic acid mono-(4-methoxy-benzyl ester) (33533-58-3)

Guidance literature:

Phthalsaeureanhydrid, p-CH3O-C6H4-CH2OH, Pyridin;

DOI:10.1039/J29710001142

upstream raw materials:

phthalic anhydride

4-Methoxybenzyl alcohol

phthalic acid 1-(4-methoxy-benzyl) ester 2-(1,2,3,4-tetrahydro-naphthalen-1-yl) ester

Downstream raw materials:

1-ethoxymethyl-4-methoxybenzene

1-methoxy-4-(tosylmethyl)benzene

4-methoxybenzyl-(4'-methylphenyl)-sulfide

Monomethyl phthalate

Refernces

• 1、 Slade, Christopher J.,Pringle, Carol A.,Sumner, Ian G.. "1,2,3,4-Tetrahydro-1-naphthyl ester as a selective protecting group for carboxylic acids". . p. 5601 - 5604. Retrieved 2007/10/03.