C₁₃H₂₀O₇S₂

Base Information

• Chemical Name: C₁₃H₂₀O₇S₂
• CAS No.: 1185984-56-8
• Molecular Formula: C₁₃H₂₀O₇S₂
• Molecular Weight: 352.43
• Mol file: 1185984-56-8.mol

Synonyms:C₁₃H₂₀O₇S₂

Chemical Property of C₁₃H₂₀O₇S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₂₀O₇S₂

There total 3 articles about C₁₃H₂₀O₇S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R)-2-phenylmethoxybutane-1,4-diol (60989-80-2) + methanesulfonyl chloride (124-63-0) → C13H20O7S2 (1185984-56-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tetasy.2012.10.004 DOI:10.1016/j.tetasy.2012.10.004

Reference yield:

dimethyl (S)-(-)-2-benzyloxybutanedioate (82130-73-2) → C13H20O7S2 (1185984-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate; calcium chloride / ethanol / 2.5 h / 0 °C

2: triethylamine / dichloromethane / 6 h / 0 °C / Inert atmosphere

With sodium tetrahydroborate; triethylamine; calcium chloride; In ethanol; dichloromethane;

DOI:10.1016/j.tetasy.2012.10.004 DOI:10.1016/j.tetasy.2012.10.004

Reference yield:

benzyl bromide (100-39-0) → C13H20O7S2 (1185984-56-8)

Guidance literature:

Multi-step reaction with 3 steps

1: silver(l) oxide / ethyl acetate / 6 h / 20 °C

2: sodium tetrahydroborate; calcium chloride / ethanol / 2.5 h / 0 °C

3: triethylamine / dichloromethane / 6 h / 0 °C / Inert atmosphere

With sodium tetrahydroborate; triethylamine; calcium chloride; silver(l) oxide; In ethanol; dichloromethane; ethyl acetate;

DOI:10.1016/j.tetasy.2012.10.004 DOI:10.1016/j.tetasy.2012.10.004

upstream raw materials:

dimethyl (S)-(-)-2-benzyloxybutanedioate

(2R)-2-phenylmethoxybutane-1,4-diol

methanesulfonyl chloride

benzyl bromide

Downstream raw materials:

(S)-(((1,4-diiodobutan-2-yl)oxy)methyl)benzene

(1S,3S)-3-(benzyloxy)-1-(p-tolyl)cyclopentanecarbonitrile

(1R,3S)-3-(benzyloxy)-1-(p-tolyl)cyclopentanecarbonitrile

1-((1R,3S)-3-(benzyloxy)-1-methylcyclopentyl)-4-methylbenzene

Refernces

• 1、 Tymtsunik, Andriy V.,Kokhan, Serhii O.,Ivon, Yevhen M.,Komarov, Igor V.,Grygorenko, Oleksandr O.. "Intramolecular functional group differentiation as a strategy for the synthesis of bridged bicyclic β-amino acids". . p. 22737 - 22748. Retrieved 2016/03/26.